Abstract
Exposure of human monocytes to Chlamydia pneumoniae resulted in a significant enhancement of matrix metalloproteinase (MMP) 1 and 9 production following stimulation with tumor necrosis factor alpha and granulocyte monocyte-colony stimulating factor. The effect of C. pneumoniae on monocyte MMPs was mediated through the induction of prostaglandin E2. These findings may have implications for atherosclerotic plaque rapture.
Original language | English (US) |
---|---|
Pages (from-to) | 632-634 |
Number of pages | 3 |
Journal | Infection and immunity |
Volume | 73 |
Issue number | 1 |
DOIs | |
State | Published - Jan 2005 |
ASJC Scopus subject areas
- Parasitology
- Microbiology
- Immunology
- Infectious Diseases