TY - JOUR
T1 - Childhood Factors Affecting Persistence and Desistence of Attention-Deficit/Hyperactivity Disorder Symptoms in Adulthood
T2 - Results From the MTA
AU - for the
AU - MTA Cooperative Group
AU - MTA Cooperative Group
AU - Roy, Arunima
AU - Hechtman, Lily
AU - Roy, Arunima
AU - Arnold, L. Eugene
AU - Sibley, Margaret H.
AU - Molina, Brooke S.G.
AU - Swanson, James M.
AU - Howard, Andrea L.
AU - Vitiello, Benedetto
AU - Severe, Joanne B.
AU - Jensen, Peter S.
AU - Arnold, L. Eugene
AU - Hoagwood, Kimberly
AU - Richters, John
AU - Vereen, Donald
AU - Hinshaw, Stephen P.
AU - Elliott, Glen R.
AU - Wells, Karen C.
AU - Epstein, Jeffery N.
AU - Murray, Desiree W.
AU - Conners, C. Keith
AU - March, John
AU - Swanson, James
AU - Wigal, Timothy
AU - Cantwell, Dennis P.
AU - Abikoff, Howard B.
AU - Hechtman, Lily
AU - Greenhill, Laurence L.
AU - Newcorn, Jeffrey H.
AU - Molina, Brooke
AU - Hoza, Betsy
AU - Pelham, William E.
AU - Gibbons, Robert D.
AU - Marcus, Sue
AU - Hur, Kwan
AU - Kraemer, Helena C.
AU - Hanley, Thomas
AU - Stern, Karen
N1 - Publisher Copyright:
© 2016 American Academy of Child and Adolescent Psychiatry
Copyright:
Copyright 2020 Elsevier B.V., All rights reserved.
PY - 2016/11/1
Y1 - 2016/11/1
N2 - Objective To determine childhood factors that predict attention-deficit/hyperactivity disorder (ADHD) persistence and desistence in adulthood. Method Regression analyses were used to determine associations between childhood factors and adult ADHD symptom persistence in 453 participants (mean age, 25 years) from the Multimodal Treatment Study of Children with ADHD (MTA). Childhood IQ, total number of comorbidities, child-perceived parenting practices, child-perceived parent−child relationships, parental mental health problems, marital problems of parents, household income levels, and parental education were assessed at a mean age of 8 years in all participants. Adult ADHD persistence was defined using DSM-5 symptom counts either with or without impairment, as well as mean ADHD symptom scores on the Conners’ Adult ADHD Rating Scale (CAARS). Age, sex, MTA site, and childhood ADHD symptoms were covaried. Results The most important childhood predictors of adult ADHD symptom persistence were initial ADHD symptom severity (odds ratio [OR] = 1.89, standard error [SE] = 0.28, p =.025), comorbidities (OR = 1.19, SE = 0.07, p =.018), and parental mental health problems (OR = 1.30, SE = 0.09, p =.003). Childhood IQ, socioeconomic status, parental education, and parent−child relationships showed no associations with adult ADHD symptom persistence. Conclusion Initial ADHD symptom severity, parental mental health, and childhood comorbidity affect persistence of ADHD symptoms into adulthood. Addressing these areas early may assist in reducing adult ADHD persistence and functioning problems.
AB - Objective To determine childhood factors that predict attention-deficit/hyperactivity disorder (ADHD) persistence and desistence in adulthood. Method Regression analyses were used to determine associations between childhood factors and adult ADHD symptom persistence in 453 participants (mean age, 25 years) from the Multimodal Treatment Study of Children with ADHD (MTA). Childhood IQ, total number of comorbidities, child-perceived parenting practices, child-perceived parent−child relationships, parental mental health problems, marital problems of parents, household income levels, and parental education were assessed at a mean age of 8 years in all participants. Adult ADHD persistence was defined using DSM-5 symptom counts either with or without impairment, as well as mean ADHD symptom scores on the Conners’ Adult ADHD Rating Scale (CAARS). Age, sex, MTA site, and childhood ADHD symptoms were covaried. Results The most important childhood predictors of adult ADHD symptom persistence were initial ADHD symptom severity (odds ratio [OR] = 1.89, standard error [SE] = 0.28, p =.025), comorbidities (OR = 1.19, SE = 0.07, p =.018), and parental mental health problems (OR = 1.30, SE = 0.09, p =.003). Childhood IQ, socioeconomic status, parental education, and parent−child relationships showed no associations with adult ADHD symptom persistence. Conclusion Initial ADHD symptom severity, parental mental health, and childhood comorbidity affect persistence of ADHD symptoms into adulthood. Addressing these areas early may assist in reducing adult ADHD persistence and functioning problems.
KW - IQ
KW - adulthood
KW - attention-deficit/hyperactivity disorder (ADHD)
KW - comorbidity
KW - family
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U2 - 10.1016/j.jaac.2016.05.027
DO - 10.1016/j.jaac.2016.05.027
M3 - Article
AN - SCOPUS:85001085881
VL - 55
SP - 937-944.e4
JO - Journal of the American Academy of Child and Adolescent Psychiatry
JF - Journal of the American Academy of Child and Adolescent Psychiatry
SN - 0890-8567
IS - 11
ER -