Childhood Adrenoleukodystrophy: Failure of Intensive Immunosuppression to Arrest Neurologic Progression

Sakkubai Naidu, Hugo W. Moser, Susan O'toole, Michael J. Bresnan, Diane Griffin

Research output: Contribution to journalArticlepeer-review

Abstract

Cyclophosphamide in a dosage of 350 to 700 mg/m2/d was administered for five to 11 days to four patients with childhood adrenoleukodystrophy (ALD) and to one patient with the adult cerebral form of the disease. The rate of neurologic progression in the four patients with childhood ALD did not differ from that of 167 untreated patients with childhood ALD surveyed previously.

Original languageEnglish (US)
Pages (from-to)846-848
Number of pages3
JournalArchives of neurology
Volume45
Issue number8
DOIs
StatePublished - Aug 1988

ASJC Scopus subject areas

  • Arts and Humanities (miscellaneous)
  • Clinical Neurology

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