Chemoprevention of colorectal cancer

Ramu Raju, Marcia Cruz-Correa

Research output: Contribution to journalArticlepeer-review

Abstract

Colorectal cancer is a major public health concern in all developed countries. Despite decades of advances in the treatment and prevention of colorectal cancer, it remains the second most common cause of cancer death. However, the optimal method for early detection remains unknown and patient compliance with screening recommendations remains poor. This has led to the development of complementary strategies, such as chemoprevention to reduce morbidity and mortality from colorectal cancer. Chemoprevention is defined as the use of specific pharmacologic or nutrient agents to prevent, reverse, or inhibit the process of carcinogenesis. This review was designed to discuss the most promising agents in colorectal chemoprevention.

Original languageEnglish (US)
Pages (from-to)113-124
Number of pages12
JournalDiseases of the Colon and Rectum
Volume49
Issue number1
DOIs
StatePublished - Jan 2006

Keywords

  • Adenomatous polyps
  • Aspirin
  • Chemoprevention
  • Colorectal cancer
  • Nonsteroidal anti-inflammatory drugs

ASJC Scopus subject areas

  • Gastroenterology

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