Chemoembolization of hepatic metastases from ocular melanoma: Assessment of response with contrast-enhanced and diffusion-weighted MRI

Manon Buijs, Josephina A. Vossen, Kelvin Hong, Christos S. Georgiades, Jean Francois H. Geschwind, Ihab R. Kamel

Research output: Contribution to journalArticlepeer-review

Abstract

OBJECTIVE. The purpose of this study was to assess the utility of assessment of tumor size and enhancement with diffusion-weighted and conventional MRI in the evaluation of response to transarterial chemoembolization therapy for metastatic ocular melanoma. CONCLUSION. In patients with ocular melanoma and liver metastasis treated with transarterial chemoembolization, functional MRI showed significant changes in the lesions. These changes included a decrease in tumor enhancement and an increase in the apparent diffusion coefficient of the tumor, suggesting increasing tumor necrosis and cell death.

Original languageEnglish (US)
Pages (from-to)285-289
Number of pages5
JournalAmerican Journal of Roentgenology
Volume191
Issue number1
DOIs
StatePublished - Jul 2008

Keywords

  • Diffusion-weighted MRI
  • Hepatic metastases
  • Liver
  • Metastatic ocular melanoma
  • Perfusion MRI
  • Transarterial chemoembolization
  • Treatment response

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging

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