Transarterial chemoembolization is a therapy that has been used since the early 1980s for liver cancer that involves delivery of chemotherapeutic agents into the hepatic artery. There are randomized controlled trials showing increased survival of patients undergoing transarterial chemoembolization versus supportive care; in fact, transarterial chemoembolization is considered the standard of care for intermediate stage hepatocellular carcinoma that is not surgically resectable. Transarterial chemoembolization is being used to treat metastatic disease to the liver as well; primary cancers include colorectal cancer, ocular melanoma, neuroendocrine cancer, and renal cell cancer. Although there are no randomized controlled trials, there are good survival data and few side-effects of transarterial chemoembolization in these instances.
- Doxorubicin eluting bead TACE
- Intra-arterial therapy
- Lipiodol-based TACE
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