Chemoembolization of Hepatic Malignancies

Nikhil Bhagat, Jean Francois Geschwind

Research output: Chapter in Book/Report/Conference proceedingChapter

Abstract

Transarterial chemoembolization is a therapy that has been used since the early 1980s for liver cancer that involves delivery of chemotherapeutic agents into the hepatic artery. There are randomized controlled trials showing increased survival of patients undergoing transarterial chemoembolization versus supportive care; in fact, transarterial chemoembolization is considered the standard of care for intermediate stage hepatocellular carcinoma that is not surgically resectable. Transarterial chemoembolization is being used to treat metastatic disease to the liver as well; primary cancers include colorectal cancer, ocular melanoma, neuroendocrine cancer, and renal cell cancer. Although there are no randomized controlled trials, there are good survival data and few side-effects of transarterial chemoembolization in these instances.

Original languageEnglish (US)
Title of host publicationUrgent Interventional Therapies
PublisherWiley-Blackwell
Pages403-409
Number of pages7
ISBN (Electronic)9781118504499
ISBN (Print)9780470672020
DOIs
StatePublished - Nov 17 2014

Keywords

  • Doxorubicin eluting bead TACE
  • Intra-arterial therapy
  • Lipiodol-based TACE

ASJC Scopus subject areas

  • Medicine(all)

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  • Cite this

    Bhagat, N., & Geschwind, J. F. (2014). Chemoembolization of Hepatic Malignancies. In Urgent Interventional Therapies (pp. 403-409). Wiley-Blackwell. https://doi.org/10.1002/9781118504499.ch46