Chemistry and behavioral studies identify chiral cyclopropanes as selective α4β2-nicotinic acetylcholine receptor partial agonists exhibiting an antidepressant profile

Hankun Zhang, Werner Tückmantel, J. Brek Eaton, Po Wai Yuen, Li Fang Yu, Krishna Mohan Bajjuri, Allison Fedolak, Daguang Wang, Afshin Ghavami, Barbara Caldarone, Neil E. Paterson, David A. Lowe, Daniela Brunner, Ronald J. Lukas, Alan P. Kozikowski