Characterizing the protein content in tears for early detection of disease

M. Antoine, P. Demirev, H. Le, Ashley Behrens, J. Castro

Research output: Contribution to journalArticle

Abstract

A team of biomedical researchers have developed new method using mass spectrometry and advanced proteomics to identify wellness biomarkers and pathogen biomarkers present in tear fluid obtained from healthy and diseased animals. Tear specimens were suitable specimens for rapid diagnosis due to their clean background and non-invasive collection. The overall objective of the research effort was to determine the feasibility of detecting and identifying biomarkers that indicated pathogen exposure and infection in tear fluid in real time. The protein content of tear samples was established by advanced analytical proteomics technologies.

Original languageEnglish (US)
Pages (from-to)228-229
Number of pages2
JournalJohns Hopkins APL Technical Digest (Applied Physics Laboratory)
Volume28
Issue number3
StatePublished - 2010

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biomarkers
Biomarkers
pathogens
Pathogens
proteins
Proteins
Fluids
fluids
infectious diseases
Mass spectrometry
animals
Animals
mass spectroscopy
Proteomics

ASJC Scopus subject areas

  • Engineering(all)
  • Physics and Astronomy(all)

Cite this

Characterizing the protein content in tears for early detection of disease. / Antoine, M.; Demirev, P.; Le, H.; Behrens, Ashley; Castro, J.

In: Johns Hopkins APL Technical Digest (Applied Physics Laboratory), Vol. 28, No. 3, 2010, p. 228-229.

Research output: Contribution to journalArticle

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