Characterizing the function of unstructured proteins: Simulations of charged polymers under confinement

Joanne N. Bright; Mark J. Stevens; Jan Hakan Hoh; Thomas B. Woolf

doi:10.1063/1.1392361

Characterizing the function of unstructured proteins: Simulations of charged polymers under confinement

Joanne N. Bright, Mark J. Stevens, Jan Hakan Hoh, Thomas B. Woolf

School of Medicine

Research output: Contribution to journal › Article › peer-review

17 Scopus citations

Abstract

Molecular dynamics (MD) simulations of neutral, charged and polyampholyte polymers within a confined geometry were performed. The simulations provided a good test of polymer predictions for finite length chains. Furthermore, these simulations suggest a previously unexplored dependence of the properties of a tethered, confined polyampholyte on the charge sequence of the chain.

Original language	English (US)
Pages (from-to)	4909-4918
Number of pages	10
Journal	Journal of Chemical Physics
Volume	115
Issue number	10
DOIs	https://doi.org/10.1063/1.1392361
State	Published - Sep 8 2001

ASJC Scopus subject areas

Physics and Astronomy(all)
Physical and Theoretical Chemistry

Access to Document

10.1063/1.1392361

Cite this

@article{77dac36518b54475af9092a7a9dd08c4,

title = "Characterizing the function of unstructured proteins: Simulations of charged polymers under confinement",

abstract = "Molecular dynamics (MD) simulations of neutral, charged and polyampholyte polymers within a confined geometry were performed. The simulations provided a good test of polymer predictions for finite length chains. Furthermore, these simulations suggest a previously unexplored dependence of the properties of a tethered, confined polyampholyte on the charge sequence of the chain.",

author = "Bright, {Joanne N.} and Stevens, {Mark J.} and Hoh, {Jan Hakan} and Woolf, {Thomas B.}",

year = "2001",

month = sep,

day = "8",

doi = "10.1063/1.1392361",

language = "English (US)",

volume = "115",

pages = "4909--4918",

journal = "Journal of Chemical Physics",

issn = "0021-9606",

publisher = "American Institute of Physics Publising LLC",

number = "10",

}

TY - JOUR

T1 - Characterizing the function of unstructured proteins

T2 - Simulations of charged polymers under confinement

AU - Bright, Joanne N.

AU - Stevens, Mark J.

AU - Hoh, Jan Hakan

AU - Woolf, Thomas B.

PY - 2001/9/8

Y1 - 2001/9/8

N2 - Molecular dynamics (MD) simulations of neutral, charged and polyampholyte polymers within a confined geometry were performed. The simulations provided a good test of polymer predictions for finite length chains. Furthermore, these simulations suggest a previously unexplored dependence of the properties of a tethered, confined polyampholyte on the charge sequence of the chain.

AB - Molecular dynamics (MD) simulations of neutral, charged and polyampholyte polymers within a confined geometry were performed. The simulations provided a good test of polymer predictions for finite length chains. Furthermore, these simulations suggest a previously unexplored dependence of the properties of a tethered, confined polyampholyte on the charge sequence of the chain.

UR - http://www.scopus.com/inward/record.url?scp=0035828344&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0035828344&partnerID=8YFLogxK

U2 - 10.1063/1.1392361

DO - 10.1063/1.1392361

M3 - Article

AN - SCOPUS:0035828344

SN - 0021-9606

VL - 115

SP - 4909

EP - 4918

JO - Journal of Chemical Physics

JF - Journal of Chemical Physics

IS - 10

ER -

Characterizing the function of unstructured proteins: Simulations of charged polymers under confinement

Abstract

ASJC Scopus subject areas

Access to Document

Other files and links

Fingerprint

Cite this