@article{5fcb732cbeca4c98a4863b98b580951f,
title = "Characterization of unrelated clinical Legionella pneumophila isolates in Catalonia by monoclonal subgrouping and sequence-based typing",
abstract = "Aim: To characterize the genetic diversity of unrelated Legionella pneumophila clinical isolates in Catalonia and compare with other European regions. Methods: 95 unrelated isolates were analyzed using monoclonal antibodies and sequence-based typing, 1989-2013. Results: The isolates showed a high diversity (IOD 0.964) with a predominance of some profiles (ST37-Phialdelphia, ST23-Philadelphia and ST1-OLDA). All regions had predominant sequence types (STs) that differed between regions, and only 3% of STs were shared between the three regions. Conclusion: L. pneumophila clinical isolates from Catalonia presented a high diversity and can be used in epidemiological surveillance studies. The heterogeneous predominance of STs between European regions suggested a relationship between geographical distribution and virulence of some STs.",
keywords = "Legionella, clinical isolates, monoclonal antibody, sequence-based typing",
author = "Marian Garcia-Nu{\~n}ez and Sara Quero and Pedro-Botet, {Maria Lluisa} and Irene Barrabeig and Josep Avarez and Irene Campoy and Sala, {Maria Rosa} and Noem{\'i} Parraga-Ni{\~n}o and Sofia Minguell and Joan Cayl{\`a} and Lourdes Mateu and Miquel Sabria",
note = "Funding Information: The present study was funded by the project PI10/0191, integrated in the National R + D + I and funded by the ISCIII-General Evalutation Branch and the European Regional Development Fund (FEDER) by CIBER de Enfermedades Respiratorias (CIBERES). CIBERES is an initiative of Instituo de Salud Carlos III. S Quero was funded by CIBERES and FI-AGAUR (FI-AGAUR 2012). The authors have no other relevant affiliations or financial involvement with any organization or entity with a financial interest in or financial conflict with the subject matter or materials discussed in the manuscript. Publisher Copyright: {\textcopyright} 2016 Future Medicine Ltd.",
year = "2016",
month = jul,
doi = "10.2217/fmb-2016-0013",
language = "English (US)",
volume = "11",
pages = "865--875",
journal = "Future Microbiology",
issn = "1746-0913",
publisher = "Future Medicine Ltd.",
number = "7",
}