Characterization of serum acid phosphatase associated with Dengue hemorrhagic fever

K. W. Lam; D. S. Burke; M. Siemens; V. Cipperly; C. Y. Li; L. T. Yam

doi:10.1093/clinchem/28.11.2296

Characterization of serum acid phosphatase associated with Dengue hemorrhagic fever

K. W. Lam, D. S. Burke, M. Siemens, V. Cipperly, C. Y. Li, L. T. Yam

Research output: Contribution to journal › Article › peer-review

3 Scopus citations

Abstract

Increases of tartrate-resistant acid phosphatase (EC 3.1.3.2) in the serum of children affected by Dengue hemorrhagic fever were detected by a colorimetric method. Immunochemical and electrophoretic methods confirmed that this increased enzyme activity is identical to that of isoenzyme 5b of osteoclasts. Ion-exchange column chromatography separated the serum acid phosphatase into two components with identical antigenicity, substrate specificity, and electrophoretic mobility. They differ in molecular size.

Original language	English (US)
Pages (from-to)	2296-2299
Number of pages	4
Journal	Unknown Journal
Volume	28
Issue number	11
DOIs	https://doi.org/10.1093/clinchem/28.11.2296
State	Published - 1982
Externally published	Yes

ASJC Scopus subject areas

Clinical Biochemistry
Biochemistry, medical

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10.1093/clinchem/28.11.2296

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AU - Lam, K. W.

AU - Burke, D. S.

AU - Siemens, M.

AU - Cipperly, V.

AU - Li, C. Y.

AU - Yam, L. T.

PY - 1982

Y1 - 1982

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AB - Increases of tartrate-resistant acid phosphatase (EC 3.1.3.2) in the serum of children affected by Dengue hemorrhagic fever were detected by a colorimetric method. Immunochemical and electrophoretic methods confirmed that this increased enzyme activity is identical to that of isoenzyme 5b of osteoclasts. Ion-exchange column chromatography separated the serum acid phosphatase into two components with identical antigenicity, substrate specificity, and electrophoretic mobility. They differ in molecular size.

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JO - Unknown Journal

JF - Unknown Journal

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ER -

Characterization of serum acid phosphatase associated with Dengue hemorrhagic fever

Abstract

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