Characterization of obstructive sleep apnea before and after tongue-lip adhesion in children with micrognathia

Ahmad R. Sedaghat, Iee Ching W Anderson, Brian M. McGinley, Mark I. Rossberg, Richard Redett, Stacey L. Ishman

Research output: Contribution to journalArticle

Abstract

Objectives: To characterize airway obstruction before and after tongue-lip adhesion in children with micrognathia using polysomnography. Design: Retrospective pilot case series. Participants and Methods: Evaluation of all children with micrognathia who underwent tongue-lip adhesion and polysomnography before and after surgery from 2002 to 2007 (N = 8). Results: Eight children met inclusion criteria; six were girls. The mean interval between polysomnography and tongue-lip adhesion was 6 days (range, 2 to 13 days) preoperatively and 17 days (range, 5 to 32 days) postoperatively. Severe obstructive sleep apnea was identified in seven of eight (88%) children, with a mean preoperative obstructive apnea hypopnea index of 52.6 events per hour (range, 7.1 to 85.7 events per hour). None had significant central sleep apneas (>5 per hour). Tongue-lip adhesion resulted in a mean decrease of 34.5 events per hour (range, -65.8 to 71.6 events per hour). After tongue-lip adhesion, seven of eight (87.5%) patients had an improved obstructive apnea hypopnea index, with resolution of obstructive sleep apnea in one child and improvement to mild (two) and moderate (two) obstructive sleep apnea in four others. Only one child had an obstructive apnea hypopnea index that increased after tongue-lip adhesion. Peak end-tidal pCO2 measurements were elevated in all eight children before surgery at a mean of 60 mm Hg (range, 52 to 76 mm Hg) that improved to 51 mm Hg (range, 45 to 59 mm Hg), with normal peak levels in four children. Oxygen saturation nadir improved from 73% (range, 58% to 81%) to 82% (range, 65% to 94%). Conclusions: Tongue-lip adhesion may be performed in micrognathic infants to alleviate airway obstruction. Polysomnographic evaluation in this pilot study before and after surgery suggests that tongue-lip adhesion usually improves obstructive sleep apnea, but only 38% had complete resolution. Future studies of tongue-lip adhesion efficacy should include polysomnographic evaluation.

Original languageEnglish (US)
Pages (from-to)21-26
Number of pages6
JournalCleft Palate-Craniofacial Journal
Volume49
Issue number1
DOIs
StatePublished - 2012

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Micrognathism
Obstructive Sleep Apnea
Lip
Tongue
Polysomnography
Apnea
Airway Obstruction
Central Sleep Apnea

Keywords

  • Micrognathia
  • OSA
  • Pierre robin
  • Tongue-lip adhesion

ASJC Scopus subject areas

  • Otorhinolaryngology
  • Oral Surgery
  • Medicine(all)

Cite this

Characterization of obstructive sleep apnea before and after tongue-lip adhesion in children with micrognathia. / Sedaghat, Ahmad R.; Anderson, Iee Ching W; McGinley, Brian M.; Rossberg, Mark I.; Redett, Richard; Ishman, Stacey L.

In: Cleft Palate-Craniofacial Journal, Vol. 49, No. 1, 2012, p. 21-26.

Research output: Contribution to journalArticle

Sedaghat, Ahmad R. ; Anderson, Iee Ching W ; McGinley, Brian M. ; Rossberg, Mark I. ; Redett, Richard ; Ishman, Stacey L. / Characterization of obstructive sleep apnea before and after tongue-lip adhesion in children with micrognathia. In: Cleft Palate-Craniofacial Journal. 2012 ; Vol. 49, No. 1. pp. 21-26.
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abstract = "Objectives: To characterize airway obstruction before and after tongue-lip adhesion in children with micrognathia using polysomnography. Design: Retrospective pilot case series. Participants and Methods: Evaluation of all children with micrognathia who underwent tongue-lip adhesion and polysomnography before and after surgery from 2002 to 2007 (N = 8). Results: Eight children met inclusion criteria; six were girls. The mean interval between polysomnography and tongue-lip adhesion was 6 days (range, 2 to 13 days) preoperatively and 17 days (range, 5 to 32 days) postoperatively. Severe obstructive sleep apnea was identified in seven of eight (88{\%}) children, with a mean preoperative obstructive apnea hypopnea index of 52.6 events per hour (range, 7.1 to 85.7 events per hour). None had significant central sleep apneas (>5 per hour). Tongue-lip adhesion resulted in a mean decrease of 34.5 events per hour (range, -65.8 to 71.6 events per hour). After tongue-lip adhesion, seven of eight (87.5{\%}) patients had an improved obstructive apnea hypopnea index, with resolution of obstructive sleep apnea in one child and improvement to mild (two) and moderate (two) obstructive sleep apnea in four others. Only one child had an obstructive apnea hypopnea index that increased after tongue-lip adhesion. Peak end-tidal pCO2 measurements were elevated in all eight children before surgery at a mean of 60 mm Hg (range, 52 to 76 mm Hg) that improved to 51 mm Hg (range, 45 to 59 mm Hg), with normal peak levels in four children. Oxygen saturation nadir improved from 73{\%} (range, 58{\%} to 81{\%}) to 82{\%} (range, 65{\%} to 94{\%}). Conclusions: Tongue-lip adhesion may be performed in micrognathic infants to alleviate airway obstruction. Polysomnographic evaluation in this pilot study before and after surgery suggests that tongue-lip adhesion usually improves obstructive sleep apnea, but only 38{\%} had complete resolution. Future studies of tongue-lip adhesion efficacy should include polysomnographic evaluation.",
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T1 - Characterization of obstructive sleep apnea before and after tongue-lip adhesion in children with micrognathia

AU - Sedaghat, Ahmad R.

AU - Anderson, Iee Ching W

AU - McGinley, Brian M.

AU - Rossberg, Mark I.

AU - Redett, Richard

AU - Ishman, Stacey L.

PY - 2012

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N2 - Objectives: To characterize airway obstruction before and after tongue-lip adhesion in children with micrognathia using polysomnography. Design: Retrospective pilot case series. Participants and Methods: Evaluation of all children with micrognathia who underwent tongue-lip adhesion and polysomnography before and after surgery from 2002 to 2007 (N = 8). Results: Eight children met inclusion criteria; six were girls. The mean interval between polysomnography and tongue-lip adhesion was 6 days (range, 2 to 13 days) preoperatively and 17 days (range, 5 to 32 days) postoperatively. Severe obstructive sleep apnea was identified in seven of eight (88%) children, with a mean preoperative obstructive apnea hypopnea index of 52.6 events per hour (range, 7.1 to 85.7 events per hour). None had significant central sleep apneas (>5 per hour). Tongue-lip adhesion resulted in a mean decrease of 34.5 events per hour (range, -65.8 to 71.6 events per hour). After tongue-lip adhesion, seven of eight (87.5%) patients had an improved obstructive apnea hypopnea index, with resolution of obstructive sleep apnea in one child and improvement to mild (two) and moderate (two) obstructive sleep apnea in four others. Only one child had an obstructive apnea hypopnea index that increased after tongue-lip adhesion. Peak end-tidal pCO2 measurements were elevated in all eight children before surgery at a mean of 60 mm Hg (range, 52 to 76 mm Hg) that improved to 51 mm Hg (range, 45 to 59 mm Hg), with normal peak levels in four children. Oxygen saturation nadir improved from 73% (range, 58% to 81%) to 82% (range, 65% to 94%). Conclusions: Tongue-lip adhesion may be performed in micrognathic infants to alleviate airway obstruction. Polysomnographic evaluation in this pilot study before and after surgery suggests that tongue-lip adhesion usually improves obstructive sleep apnea, but only 38% had complete resolution. Future studies of tongue-lip adhesion efficacy should include polysomnographic evaluation.

AB - Objectives: To characterize airway obstruction before and after tongue-lip adhesion in children with micrognathia using polysomnography. Design: Retrospective pilot case series. Participants and Methods: Evaluation of all children with micrognathia who underwent tongue-lip adhesion and polysomnography before and after surgery from 2002 to 2007 (N = 8). Results: Eight children met inclusion criteria; six were girls. The mean interval between polysomnography and tongue-lip adhesion was 6 days (range, 2 to 13 days) preoperatively and 17 days (range, 5 to 32 days) postoperatively. Severe obstructive sleep apnea was identified in seven of eight (88%) children, with a mean preoperative obstructive apnea hypopnea index of 52.6 events per hour (range, 7.1 to 85.7 events per hour). None had significant central sleep apneas (>5 per hour). Tongue-lip adhesion resulted in a mean decrease of 34.5 events per hour (range, -65.8 to 71.6 events per hour). After tongue-lip adhesion, seven of eight (87.5%) patients had an improved obstructive apnea hypopnea index, with resolution of obstructive sleep apnea in one child and improvement to mild (two) and moderate (two) obstructive sleep apnea in four others. Only one child had an obstructive apnea hypopnea index that increased after tongue-lip adhesion. Peak end-tidal pCO2 measurements were elevated in all eight children before surgery at a mean of 60 mm Hg (range, 52 to 76 mm Hg) that improved to 51 mm Hg (range, 45 to 59 mm Hg), with normal peak levels in four children. Oxygen saturation nadir improved from 73% (range, 58% to 81%) to 82% (range, 65% to 94%). Conclusions: Tongue-lip adhesion may be performed in micrognathic infants to alleviate airway obstruction. Polysomnographic evaluation in this pilot study before and after surgery suggests that tongue-lip adhesion usually improves obstructive sleep apnea, but only 38% had complete resolution. Future studies of tongue-lip adhesion efficacy should include polysomnographic evaluation.

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KW - Pierre robin

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