Characterization of Medication Use in a Multicenter Sample of Pediatric Inpatients with Autism Spectrum Disorder

Logan K. Wink, Ernest V. Pedapati, Ryan Adams, Craig A. Erickson, Kahsi A. Pedersen, Eric M. Morrow, Desmond Kaplan, Matthew Siegel, Matthew Siegel, Craig Erickson, Robin L. Gabriels, Desmond Kaplan, Carla Mazefsky, Eric M. Morrow, Giulia Righi, Susan L. Santangelo, Logan Wink, Jill Benevides, Carol Beresford, Carrie Best & 41 others Katie Bowen, Briar Dechant, Tom Flis, Holly Gastgeb, Angela Geer, Louis Hagopian, Benjamin Handen, Adam Klever, Martin Lubetsky, Kristen MacKenzie, Zenoa Meservy, John McGonigle, Kelly McGuire, Faith McNeil, Joshua Montrenes, Tamara Palka, Ernest Pedapati, Kahsi A. Pedersen, Christine Peura, Joseph Pierri, Christie Rogers, Brad Rossman, Jennifer Ruberg, Elise Sannar, Cathleen Small, Nicole Stuckey, Barbara Tylenda, Mary Verdi, Jessica Vezzoli, Deanna Williams, Diane Williams, Donald L.St Germain, Girard Robinson, Connie Kasari, Bryan King, James McCracken, Christopher McDougle, Lawrence Scahill, Robert Schultz, Helen Tager-Flusberg,

Research output: Contribution to journalArticle

Abstract

Nearly 11% of youth with Autism Spectrum Disorder (ASD) undergo psychiatric hospitalization, and 65% are treated with psychotropic medication. Here we characterize psychotropic medication usage in subjects enrolled in the Autism Inpatient Collection. Participant psychotropic medication usage rates topped 90% at admission and discharge, though there was a decline at 2-month follow-up. Antipsychotics, ADHD medications, and sleep aids were the most commonly reported classes of medications. The impact of age, gender, and non-verbal IQ on medication usage rates was minimal, though age and IQ may play a role in prescribing practices. Future work is indicated to explore medication usage trends, the impact of clinical factors on medication use rates, and the safety of psychotropic medications in youth with ASD.

Original languageEnglish (US)
Pages (from-to)1-9
Number of pages9
JournalJournal of Autism and Developmental Disorders
DOIs
StateAccepted/In press - May 17 2017

Fingerprint

Pervasive Child Development Disorders
Inpatients
Pediatrics
Autistic Disorder
Antipsychotic Agents
Psychiatry
Sleep
Hospitalization
Safety

Keywords

  • Antipsychotics
  • Autism
  • Autism Spectrum Disorder
  • Medication
  • Psychiatric hospitalization

ASJC Scopus subject areas

  • Developmental and Educational Psychology

Cite this

Wink, L. K., Pedapati, E. V., Adams, R., Erickson, C. A., Pedersen, K. A., Morrow, E. M., ... For The Autism And Developmental Disorders Inpatient Research Collaborative (Addirc) (2017). Characterization of Medication Use in a Multicenter Sample of Pediatric Inpatients with Autism Spectrum Disorder. Journal of Autism and Developmental Disorders, 1-9. DOI: 10.1007/s10803-017-3153-x

Characterization of Medication Use in a Multicenter Sample of Pediatric Inpatients with Autism Spectrum Disorder. / Wink, Logan K.; Pedapati, Ernest V.; Adams, Ryan; Erickson, Craig A.; Pedersen, Kahsi A.; Morrow, Eric M.; Kaplan, Desmond; Siegel, Matthew; Siegel, Matthew; Erickson, Craig; Gabriels, Robin L.; Kaplan, Desmond; Mazefsky, Carla; Morrow, Eric M.; Righi, Giulia; Santangelo, Susan L.; Wink, Logan; Benevides, Jill; Beresford, Carol; Best, Carrie; Bowen, Katie; Dechant, Briar; Flis, Tom; Gastgeb, Holly; Geer, Angela; Hagopian, Louis; Handen, Benjamin; Klever, Adam; Lubetsky, Martin; MacKenzie, Kristen; Meservy, Zenoa; McGonigle, John; McGuire, Kelly; McNeil, Faith; Montrenes, Joshua; Palka, Tamara; Pedapati, Ernest; Pedersen, Kahsi A.; Peura, Christine; Pierri, Joseph; Rogers, Christie; Rossman, Brad; Ruberg, Jennifer; Sannar, Elise; Small, Cathleen; Stuckey, Nicole; Tylenda, Barbara; Verdi, Mary; Vezzoli, Jessica; Williams, Deanna; Williams, Diane; Germain, Donald L.St; Robinson, Girard; Kasari, Connie; King, Bryan; McCracken, James; McDougle, Christopher; Scahill, Lawrence; Schultz, Robert; Tager-Flusberg, Helen; For The Autism And Developmental Disorders Inpatient Research Collaborative (Addirc).

In: Journal of Autism and Developmental Disorders, 17.05.2017, p. 1-9.

Research output: Contribution to journalArticle

Wink, LK, Pedapati, EV, Adams, R, Erickson, CA, Pedersen, KA, Morrow, EM, Kaplan, D, Siegel, M, Siegel, M, Erickson, C, Gabriels, RL, Kaplan, D, Mazefsky, C, Morrow, EM, Righi, G, Santangelo, SL, Wink, L, Benevides, J, Beresford, C, Best, C, Bowen, K, Dechant, B, Flis, T, Gastgeb, H, Geer, A, Hagopian, L, Handen, B, Klever, A, Lubetsky, M, MacKenzie, K, Meservy, Z, McGonigle, J, McGuire, K, McNeil, F, Montrenes, J, Palka, T, Pedapati, E, Pedersen, KA, Peura, C, Pierri, J, Rogers, C, Rossman, B, Ruberg, J, Sannar, E, Small, C, Stuckey, N, Tylenda, B, Verdi, M, Vezzoli, J, Williams, D, Williams, D, Germain, DLS, Robinson, G, Kasari, C, King, B, McCracken, J, McDougle, C, Scahill, L, Schultz, R, Tager-Flusberg, H & For The Autism And Developmental Disorders Inpatient Research Collaborative (Addirc) 2017, 'Characterization of Medication Use in a Multicenter Sample of Pediatric Inpatients with Autism Spectrum Disorder' Journal of Autism and Developmental Disorders, pp. 1-9. DOI: 10.1007/s10803-017-3153-x

Wink, Logan K.; Pedapati, Ernest V.; Adams, Ryan; Erickson, Craig A.; Pedersen, Kahsi A.; Morrow, Eric M.; Kaplan, Desmond; Siegel, Matthew; Siegel, Matthew; Erickson, Craig; Gabriels, Robin L.; Kaplan, Desmond; Mazefsky, Carla; Morrow, Eric M.; Righi, Giulia; Santangelo, Susan L.; Wink, Logan; Benevides, Jill; Beresford, Carol; Best, Carrie; Bowen, Katie; Dechant, Briar; Flis, Tom; Gastgeb, Holly; Geer, Angela; Hagopian, Louis; Handen, Benjamin; Klever, Adam; Lubetsky, Martin; MacKenzie, Kristen; Meservy, Zenoa; McGonigle, John; McGuire, Kelly; McNeil, Faith; Montrenes, Joshua; Palka, Tamara; Pedapati, Ernest; Pedersen, Kahsi A.; Peura, Christine; Pierri, Joseph; Rogers, Christie; Rossman, Brad; Ruberg, Jennifer; Sannar, Elise; Small, Cathleen; Stuckey, Nicole; Tylenda, Barbara; Verdi, Mary; Vezzoli, Jessica; Williams, Deanna; Williams, Diane; Germain, Donald L.St; Robinson, Girard; Kasari, Connie; King, Bryan; McCracken, James; McDougle, Christopher; Scahill, Lawrence; Schultz, Robert; Tager-Flusberg, Helen; For The Autism And Developmental Disorders Inpatient Research Collaborative (Addirc) / Characterization of Medication Use in a Multicenter Sample of Pediatric Inpatients with Autism Spectrum Disorder.

In: Journal of Autism and Developmental Disorders, 17.05.2017, p. 1-9.

Research output: Contribution to journalArticle

@article{2efc7d9136014415953416ce12ef6e66,
title = "Characterization of Medication Use in a Multicenter Sample of Pediatric Inpatients with Autism Spectrum Disorder",
abstract = "Nearly 11% of youth with Autism Spectrum Disorder (ASD) undergo psychiatric hospitalization, and 65% are treated with psychotropic medication. Here we characterize psychotropic medication usage in subjects enrolled in the Autism Inpatient Collection. Participant psychotropic medication usage rates topped 90% at admission and discharge, though there was a decline at 2-month follow-up. Antipsychotics, ADHD medications, and sleep aids were the most commonly reported classes of medications. The impact of age, gender, and non-verbal IQ on medication usage rates was minimal, though age and IQ may play a role in prescribing practices. Future work is indicated to explore medication usage trends, the impact of clinical factors on medication use rates, and the safety of psychotropic medications in youth with ASD.",
keywords = "Antipsychotics, Autism, Autism Spectrum Disorder, Medication, Psychiatric hospitalization",
author = "Wink, {Logan K.} and Pedapati, {Ernest V.} and Ryan Adams and Erickson, {Craig A.} and Pedersen, {Kahsi A.} and Morrow, {Eric M.} and Desmond Kaplan and Matthew Siegel and Matthew Siegel and Craig Erickson and Gabriels, {Robin L.} and Desmond Kaplan and Carla Mazefsky and Morrow, {Eric M.} and Giulia Righi and Santangelo, {Susan L.} and Logan Wink and Jill Benevides and Carol Beresford and Carrie Best and Katie Bowen and Briar Dechant and Tom Flis and Holly Gastgeb and Angela Geer and Louis Hagopian and Benjamin Handen and Adam Klever and Martin Lubetsky and Kristen MacKenzie and Zenoa Meservy and John McGonigle and Kelly McGuire and Faith McNeil and Joshua Montrenes and Tamara Palka and Ernest Pedapati and Pedersen, {Kahsi A.} and Christine Peura and Joseph Pierri and Christie Rogers and Brad Rossman and Jennifer Ruberg and Elise Sannar and Cathleen Small and Nicole Stuckey and Barbara Tylenda and Mary Verdi and Jessica Vezzoli and Deanna Williams and Diane Williams and Germain, {Donald L.St} and Girard Robinson and Connie Kasari and Bryan King and James McCracken and Christopher McDougle and Lawrence Scahill and Robert Schultz and Helen Tager-Flusberg and {For The Autism And Developmental Disorders Inpatient Research Collaborative (Addirc)}",
year = "2017",
month = "5",
doi = "10.1007/s10803-017-3153-x",
pages = "1--9",
journal = "Journal of Autism and Developmental Disorders",
issn = "0162-3257",
publisher = "Springer New York",

}

TY - JOUR

T1 - Characterization of Medication Use in a Multicenter Sample of Pediatric Inpatients with Autism Spectrum Disorder

AU - Wink,Logan K.

AU - Pedapati,Ernest V.

AU - Adams,Ryan

AU - Erickson,Craig A.

AU - Pedersen,Kahsi A.

AU - Morrow,Eric M.

AU - Kaplan,Desmond

AU - Siegel,Matthew

AU - Siegel,Matthew

AU - Erickson,Craig

AU - Gabriels,Robin L.

AU - Kaplan,Desmond

AU - Mazefsky,Carla

AU - Morrow,Eric M.

AU - Righi,Giulia

AU - Santangelo,Susan L.

AU - Wink,Logan

AU - Benevides,Jill

AU - Beresford,Carol

AU - Best,Carrie

AU - Bowen,Katie

AU - Dechant,Briar

AU - Flis,Tom

AU - Gastgeb,Holly

AU - Geer,Angela

AU - Hagopian,Louis

AU - Handen,Benjamin

AU - Klever,Adam

AU - Lubetsky,Martin

AU - MacKenzie,Kristen

AU - Meservy,Zenoa

AU - McGonigle,John

AU - McGuire,Kelly

AU - McNeil,Faith

AU - Montrenes,Joshua

AU - Palka,Tamara

AU - Pedapati,Ernest

AU - Pedersen,Kahsi A.

AU - Peura,Christine

AU - Pierri,Joseph

AU - Rogers,Christie

AU - Rossman,Brad

AU - Ruberg,Jennifer

AU - Sannar,Elise

AU - Small,Cathleen

AU - Stuckey,Nicole

AU - Tylenda,Barbara

AU - Verdi,Mary

AU - Vezzoli,Jessica

AU - Williams,Deanna

AU - Williams,Diane

AU - Germain,Donald L.St

AU - Robinson,Girard

AU - Kasari,Connie

AU - King,Bryan

AU - McCracken,James

AU - McDougle,Christopher

AU - Scahill,Lawrence

AU - Schultz,Robert

AU - Tager-Flusberg,Helen

AU - For The Autism And Developmental Disorders Inpatient Research Collaborative (Addirc)

PY - 2017/5/17

Y1 - 2017/5/17

N2 - Nearly 11% of youth with Autism Spectrum Disorder (ASD) undergo psychiatric hospitalization, and 65% are treated with psychotropic medication. Here we characterize psychotropic medication usage in subjects enrolled in the Autism Inpatient Collection. Participant psychotropic medication usage rates topped 90% at admission and discharge, though there was a decline at 2-month follow-up. Antipsychotics, ADHD medications, and sleep aids were the most commonly reported classes of medications. The impact of age, gender, and non-verbal IQ on medication usage rates was minimal, though age and IQ may play a role in prescribing practices. Future work is indicated to explore medication usage trends, the impact of clinical factors on medication use rates, and the safety of psychotropic medications in youth with ASD.

AB - Nearly 11% of youth with Autism Spectrum Disorder (ASD) undergo psychiatric hospitalization, and 65% are treated with psychotropic medication. Here we characterize psychotropic medication usage in subjects enrolled in the Autism Inpatient Collection. Participant psychotropic medication usage rates topped 90% at admission and discharge, though there was a decline at 2-month follow-up. Antipsychotics, ADHD medications, and sleep aids were the most commonly reported classes of medications. The impact of age, gender, and non-verbal IQ on medication usage rates was minimal, though age and IQ may play a role in prescribing practices. Future work is indicated to explore medication usage trends, the impact of clinical factors on medication use rates, and the safety of psychotropic medications in youth with ASD.

KW - Antipsychotics

KW - Autism

KW - Autism Spectrum Disorder

KW - Medication

KW - Psychiatric hospitalization

UR - http://www.scopus.com/inward/record.url?scp=85019543395&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=85019543395&partnerID=8YFLogxK

U2 - 10.1007/s10803-017-3153-x

DO - 10.1007/s10803-017-3153-x

M3 - Article

SP - 1

EP - 9

JO - Journal of Autism and Developmental Disorders

T2 - Journal of Autism and Developmental Disorders

JF - Journal of Autism and Developmental Disorders

SN - 0162-3257

ER -