@article{2efc7d9136014415953416ce12ef6e66,
title = "Characterization of Medication Use in a Multicenter Sample of Pediatric Inpatients with Autism Spectrum Disorder",
abstract = "Nearly 11% of youth with Autism Spectrum Disorder (ASD) undergo psychiatric hospitalization, and 65% are treated with psychotropic medication. Here we characterize psychotropic medication usage in subjects enrolled in the Autism Inpatient Collection. Participant psychotropic medication usage rates topped 90% at admission and discharge, though there was a decline at 2-month follow-up. Antipsychotics, ADHD medications, and sleep aids were the most commonly reported classes of medications. The impact of age, gender, and non-verbal IQ on medication usage rates was minimal, though age and IQ may play a role in prescribing practices. Future work is indicated to explore medication usage trends, the impact of clinical factors on medication use rates, and the safety of psychotropic medications in youth with ASD.",
keywords = "Antipsychotics, Autism, Autism Spectrum Disorder, Medication, Psychiatric hospitalization",
author = "{For The Autism And Developmental Disorders Inpatient Research Collaborative (Addirc)} and Wink, {Logan K.} and Pedapati, {Ernest V.} and Ryan Adams and Erickson, {Craig A.} and Pedersen, {Kahsi A.} and Morrow, {Eric M.} and Desmond Kaplan and Matthew Siegel and Matthew Siegel and Craig Erickson and Gabriels, {Robin L.} and Desmond Kaplan and Carla Mazefsky and Morrow, {Eric M.} and Giulia Righi and Santangelo, {Susan L.} and Logan Wink and Jill Benevides and Carol Beresford and Carrie Best and Katie Bowen and Briar Dechant and Tom Flis and Holly Gastgeb and Angela Geer and Louis Hagopian and Benjamin Handen and Adam Klever and Martin Lubetsky and Kristen MacKenzie and Zenoa Meservy and John McGonigle and Kelly McGuire and Faith McNeil and Joshua Montrenes and Tamara Palka and Ernest Pedapati and Pedersen, {Kahsi A.} and Christine Peura and Joseph Pierri and Christie Rogers and Brad Rossman and Jennifer Ruberg and Elise Sannar and Cathleen Small and Nicole Stuckey and Barbara Tylenda and Mary Verdi and Jessica Vezzoli and Deanna Williams",
note = "Funding Information: Funding The Autism Inpatient Collection (AIC) phenotypic database and biorepository is supported by a grant from the Simons Foundation Autism Research Initiative and the Nancy Lurie Marks Family Foundation, (SFARI #296318 to M.S.). Funding Information: Conflict of interest The authors report no direct conflicts of interest with this report. Dr. Wink{\textquoteright}s current research is supported by the Si-mons Research Foundation, Autism Speaks, Riovant Sciences Ltd, and Cures Within Reach. Dr. Pedapati receives research support from the Cincinnati Children{\textquoteright}s Hospital Research Foundation. Dr. Erickson is a consultant to and holds equity in Confluence Pharmaceuticals and is a consultant to Neurotrope and Fulcrum. Dr. Erickson is a past consultant to Alcobra Pharmaceuticals, the Roche Group, and Novartis. Dr. Erickson holds non-related IP held by CCHMC and Indiana University. Dr. Erickson receives or has received research grant support from the John Merck Fund, Indiana University School of Medicine, Cincinnati Children{\textquoteright}s Hospital Medical Center, Autism Speaks, the United States Department of Defense, the Simons Foundation, the United States Centers for Disease Control, the National Fragile X Foundation, The Roche Group, Neuren Pharmaceuticals, the National Institutes of Health, and Riovant Sciences Ltd. Dr. Morrow is supported by the National Institute of Mental Health (R01 MH105442) and a grant from the Simons Foundation Autism Research Initiative (SFARI #286756 to EMM). Dr. Kaplan and Dr. Siegel report no conflicts of interest.",
year = "2018",
month = nov,
day = "1",
doi = "10.1007/s10803-017-3153-x",
language = "English (US)",
volume = "48",
pages = "3711--3719",
journal = "Journal of Autism and Developmental Disorders",
issn = "0162-3257",
publisher = "Springer New York",
number = "11",
}