TY - JOUR
T1 - Characterization of a trichophyton mentagrophytes and its diffusible pigment
AU - Merz, W. G.
AU - Lloyd, K. O.
AU - Silva-Hutner, Margarita
PY - 1972
Y1 - 1972
N2 - A clinical isolate of Trichophyton mentagrophytes which produces a diffusible red-brown pigment as well as typical microconidia en grappe and abundant spirals on Sabouraud's Dextrose Agar has been studied. It splits urea and perforates hair in vitro but does not produce pigment on cornmeal agar or require vitamins for growth. A low molecular weight, red pigment, partially purified from culture filtrates by gel-filtration, was characterized as 2-carboxy 2,3-dihydroindole-5,6-quinone, an intermediate in melanin biosynthesis. It is water soluble, lacks free amino groups, unstable in alkaline buffers, and has spectral absorption peaks at 320-340 nm and 450-490 nm.
AB - A clinical isolate of Trichophyton mentagrophytes which produces a diffusible red-brown pigment as well as typical microconidia en grappe and abundant spirals on Sabouraud's Dextrose Agar has been studied. It splits urea and perforates hair in vitro but does not produce pigment on cornmeal agar or require vitamins for growth. A low molecular weight, red pigment, partially purified from culture filtrates by gel-filtration, was characterized as 2-carboxy 2,3-dihydroindole-5,6-quinone, an intermediate in melanin biosynthesis. It is water soluble, lacks free amino groups, unstable in alkaline buffers, and has spectral absorption peaks at 320-340 nm and 450-490 nm.
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U2 - 10.1080/00362177285190171
DO - 10.1080/00362177285190171
M3 - Article
AN - SCOPUS:84907127916
SN - 1369-3786
VL - 10
SP - 86
EP - 93
JO - Medical mycology
JF - Medical mycology
IS - 1
ER -