Characteristics of the multiplication of dapsone-resistant strains of Mycobacterium leprae in mice

M. Christian, M. J. Colston, G. A. Ellard, C. A.P. Ferracci, J. H. Grosset, G. Grossetete, C. G.S. Iyer, J. Baohong, K. Lwin, D. L. Leiker, L. Levy, S. K. Noordeen, S. R. Pattyn, J. M.H. Pearson, R. J.W. Rees, H. Sansarricq, P. S. Seshadri, J. K. Seydel, C. C. Shepard, M. F.R. Waters

Research output: Contribution to journalArticlepeer-review

Abstract

Twenty-seven per cent of the 49 strains of Mycobacterium leprae isolated in the course of the THELEP controlled clinical trials of combined chemotherapy of leprosy in Bamako and Chingleput, and found to be resistance to dapsone multiplied in significantly fewer mice administered dapsone than in mice administerd the dapsone-free diet.

Original languageEnglish (US)
Pages (from-to)5-10
Number of pages6
JournalLeprosy review
Volume59
Issue number1
StatePublished - Jan 1 1988

ASJC Scopus subject areas

  • Dermatology
  • Infectious Diseases

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