Characteristics of microbes most likely to cause pandemics and global catastrophes

Amesh A. Adalja, Matthew Watson, Eric S. Toner, Anita Cicero, Thomas V. Inglesby

Research output: Chapter in Book/Report/Conference proceedingChapter

Abstract

Predicting which pathogen will confer the highest global catastrophic biological risk (GCBR) of a pandemic is a difficult task. Many approaches are retrospective and premised on prior pandemics; however, such an approach may fail to appreciate novel threats that do not have exact historical precedent. In this paper, based on a study and project we undertook, a new paradigm for pandemic preparedness is presented. This paradigm seeks to root pandemic risk in actual attributes possessed by specific classes of microbial organisms and leads to specific recommendations to augment preparedness activities.

Original languageEnglish (US)
Title of host publicationCurrent Topics in Microbiology and Immunology
PublisherSpringer
Pages1-20
Number of pages20
DOIs
StatePublished - Jan 1 2019

Publication series

NameCurrent Topics in Microbiology and Immunology
Volume424
ISSN (Print)0070-217X
ISSN (Electronic)2196-9965

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ASJC Scopus subject areas

  • Immunology and Allergy
  • Microbiology
  • Immunology
  • Microbiology (medical)

Cite this

Adalja, A. A., Watson, M., Toner, E. S., Cicero, A., & Inglesby, T. V. (2019). Characteristics of microbes most likely to cause pandemics and global catastrophes. In Current Topics in Microbiology and Immunology (pp. 1-20). (Current Topics in Microbiology and Immunology; Vol. 424). Springer. https://doi.org/10.1007/82_2019_176