Abstract
Background: There are few data regarding the use and outcomes of Breast Imaging Reporting and Data System (BI-RADS) 3 assessment on breast magnetic resonance imaging (MRI). The aim of this study was to describe the imaging findings prompting a BI-RADS 3 assessment and to report their outcomes, including the timing of follow-up examinations. Patients and Methods: We performed a retrospective study evaluating 199 breast lesions in 186 patients who were assigned a BI-RADS 3 assessment on breast MRI over a 5-year period. Clinical and imaging features were recorded. For outcomes analysis, lesions were considered benign if they showed 2 years of MRI stability, if they were declared benign during follow-up, or if the patient underwent biopsy with benign pathology results. Clinical and imaging features of BI-RADS 3 lesions associated with malignancy were assessed by the Fisher exact test, with P < .05 considered significant. Results: Of the 199 breast MRI lesions assigned a BI-RADS 3 assessment, 80 (40%) of 199 were non–mass enhancement, 61 (31%) were a single focus, and 58 (29%) were masses. A total of 131 lesions (66%) were eligible for outcome analysis after excluding those lost to follow-up; 4 (3%) were diagnosed as malignant within the 2-year follow-up. Masses assigned a BI-RADS 3 assessment were more likely to be malignant during follow-up than non–mass enhancement or single focus (P < .05). Conclusion: Despite limited data on the use of BI-RADS 3 at breast MRI, there is a low malignancy rate of 3% at our institution. Additional studies are needed to further define the appropriate use of BI-RADS 3 on breast MRI. In a study of the imaging findings prompting a Breast Imaging Reporting and Data System (BI-RADS) 3 assessment and reports of their outcomes, we assessed 199 breast MRI lesions assigned a BI-RADS 3 assessment. Of these, 80 (40%) of 199 were non–mass enhancement, 61 (31%) of 199 were a single focus and 58 (29%) of 199 were masses; of the 131 lesions with appropriate follow-up, 4 (3%) were diagnosed as malignant within a 2-year follow-up period. Despite limited data on the use of BI-RADS 3 at breast MRI, there is a low malignancy rate of 3%.
| Original language | English (US) |
|---|---|
| Journal | Clinical Breast Cancer |
| DOIs | |
| State | Accepted/In press - Jan 1 2018 |
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Keywords
- Magnetic resonance imaging
- Malignancy rate
- Short term follow-up
ASJC Scopus subject areas
- Oncology
- Cancer Research
Cite this
Characteristics and Outcomes of BI-RADS 3 Lesions on Breast MRI. / Panigrahi, Babita; Harvey, Susan; Mullen, Lisa; Falomo, Eniola; Di Carlo, Philip; Lee, Bonmyong; Myers, Kelly.
In: Clinical Breast Cancer, 01.01.2018.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Characteristics and Outcomes of BI-RADS 3 Lesions on Breast MRI
AU - Panigrahi, Babita
AU - Harvey, Susan
AU - Mullen, Lisa
AU - Falomo, Eniola
AU - Di Carlo, Philip
AU - Lee, Bonmyong
AU - Myers, Kelly
PY - 2018/1/1
Y1 - 2018/1/1
N2 - Background: There are few data regarding the use and outcomes of Breast Imaging Reporting and Data System (BI-RADS) 3 assessment on breast magnetic resonance imaging (MRI). The aim of this study was to describe the imaging findings prompting a BI-RADS 3 assessment and to report their outcomes, including the timing of follow-up examinations. Patients and Methods: We performed a retrospective study evaluating 199 breast lesions in 186 patients who were assigned a BI-RADS 3 assessment on breast MRI over a 5-year period. Clinical and imaging features were recorded. For outcomes analysis, lesions were considered benign if they showed 2 years of MRI stability, if they were declared benign during follow-up, or if the patient underwent biopsy with benign pathology results. Clinical and imaging features of BI-RADS 3 lesions associated with malignancy were assessed by the Fisher exact test, with P < .05 considered significant. Results: Of the 199 breast MRI lesions assigned a BI-RADS 3 assessment, 80 (40%) of 199 were non–mass enhancement, 61 (31%) were a single focus, and 58 (29%) were masses. A total of 131 lesions (66%) were eligible for outcome analysis after excluding those lost to follow-up; 4 (3%) were diagnosed as malignant within the 2-year follow-up. Masses assigned a BI-RADS 3 assessment were more likely to be malignant during follow-up than non–mass enhancement or single focus (P < .05). Conclusion: Despite limited data on the use of BI-RADS 3 at breast MRI, there is a low malignancy rate of 3% at our institution. Additional studies are needed to further define the appropriate use of BI-RADS 3 on breast MRI. In a study of the imaging findings prompting a Breast Imaging Reporting and Data System (BI-RADS) 3 assessment and reports of their outcomes, we assessed 199 breast MRI lesions assigned a BI-RADS 3 assessment. Of these, 80 (40%) of 199 were non–mass enhancement, 61 (31%) of 199 were a single focus and 58 (29%) of 199 were masses; of the 131 lesions with appropriate follow-up, 4 (3%) were diagnosed as malignant within a 2-year follow-up period. Despite limited data on the use of BI-RADS 3 at breast MRI, there is a low malignancy rate of 3%.
AB - Background: There are few data regarding the use and outcomes of Breast Imaging Reporting and Data System (BI-RADS) 3 assessment on breast magnetic resonance imaging (MRI). The aim of this study was to describe the imaging findings prompting a BI-RADS 3 assessment and to report their outcomes, including the timing of follow-up examinations. Patients and Methods: We performed a retrospective study evaluating 199 breast lesions in 186 patients who were assigned a BI-RADS 3 assessment on breast MRI over a 5-year period. Clinical and imaging features were recorded. For outcomes analysis, lesions were considered benign if they showed 2 years of MRI stability, if they were declared benign during follow-up, or if the patient underwent biopsy with benign pathology results. Clinical and imaging features of BI-RADS 3 lesions associated with malignancy were assessed by the Fisher exact test, with P < .05 considered significant. Results: Of the 199 breast MRI lesions assigned a BI-RADS 3 assessment, 80 (40%) of 199 were non–mass enhancement, 61 (31%) were a single focus, and 58 (29%) were masses. A total of 131 lesions (66%) were eligible for outcome analysis after excluding those lost to follow-up; 4 (3%) were diagnosed as malignant within the 2-year follow-up. Masses assigned a BI-RADS 3 assessment were more likely to be malignant during follow-up than non–mass enhancement or single focus (P < .05). Conclusion: Despite limited data on the use of BI-RADS 3 at breast MRI, there is a low malignancy rate of 3% at our institution. Additional studies are needed to further define the appropriate use of BI-RADS 3 on breast MRI. In a study of the imaging findings prompting a Breast Imaging Reporting and Data System (BI-RADS) 3 assessment and reports of their outcomes, we assessed 199 breast MRI lesions assigned a BI-RADS 3 assessment. Of these, 80 (40%) of 199 were non–mass enhancement, 61 (31%) of 199 were a single focus and 58 (29%) of 199 were masses; of the 131 lesions with appropriate follow-up, 4 (3%) were diagnosed as malignant within a 2-year follow-up period. Despite limited data on the use of BI-RADS 3 at breast MRI, there is a low malignancy rate of 3%.
KW - Magnetic resonance imaging
KW - Malignancy rate
KW - Short term follow-up
UR - http://www.scopus.com/inward/record.url?scp=85053879308&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=85053879308&partnerID=8YFLogxK
U2 - 10.1016/j.clbc.2018.08.011
DO - 10.1016/j.clbc.2018.08.011
M3 - Article
C2 - 30268764
AN - SCOPUS:85053879308
JO - Clinical Breast Cancer
JF - Clinical Breast Cancer
SN - 1526-8209
ER -