Chapter 4: Burden and management of non-cancerous HPV-related conditions: HPV-6/11 disease

Charles J.N. Lacey, Catherine M. Lowndes, Keerti V. Shah

Research output: Contribution to journalArticlepeer-review

405 Scopus citations

Abstract

Human Papillomavirus (HPV)-6 and -11 are the causative agents of ano-genital warts (GWs) and recurrent respiratory papillomatosis (RRP). They are low-risk HPV types that are uncommonly found in malignant lesions. GWs are an extremely prevalent sexually transmitted disease, whereas RRP is a rare disease that can be life threatening and requires multiple surgical procedures. GWs and RRP cause substantial healthcare costs. A quadrivalent HPV-6/11/16/18 vaccine (Merck/SPMSD) has shown essentially 100% protection against GWs in women in early studies. Cost-effectiveness analyses are needed to assess the benefits of the HPV-6/11 virus-like particle (VLP) components of the quadrivalent vaccine in population-based vaccination programmes.

Original languageEnglish (US)
Pages (from-to)S35-S41
JournalVaccine
Volume24
Issue numberSUPPL. 3
DOIs
StatePublished - Aug 21 2006
Externally publishedYes

Keywords

  • HPV-6/11
  • Management
  • Non-cancerous

ASJC Scopus subject areas

  • Molecular Medicine
  • General Immunology and Microbiology
  • General Veterinary
  • Public Health, Environmental and Occupational Health
  • Infectious Diseases

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