Chapter 19 Estrogen in Systemic Lupus Erythematosus: Lessons from the SELENA Study

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Abstract

There is a strong female predominance in SLE, implicating estrogens in the pathogenesis of disease. However, recent studies have shown that exogenous estrogens, given as oral contraceptives or HRT, do not increase the risk of mild or moderate flares in women with SLE. These and other studies provide physicians with new evidence for the rational use of estrogen therapy in women with SLE. {A textbox is presented}.

Original languageEnglish (US)
Pages (from-to)223-227
Number of pages5
JournalHandbook of Systemic Autoimmune Diseases
Volume9
DOIs
StatePublished - 2008

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Systemic Lupus Erythematosus
Estrogens
Oral Contraceptives
Physicians
Therapeutics

ASJC Scopus subject areas

  • Immunology
  • Endocrinology, Diabetes and Metabolism
  • Immunology and Allergy

Cite this

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title = "Chapter 19 Estrogen in Systemic Lupus Erythematosus: Lessons from the SELENA Study",
abstract = "There is a strong female predominance in SLE, implicating estrogens in the pathogenesis of disease. However, recent studies have shown that exogenous estrogens, given as oral contraceptives or HRT, do not increase the risk of mild or moderate flares in women with SLE. These and other studies provide physicians with new evidence for the rational use of estrogen therapy in women with SLE. {A textbox is presented}.",
author = "Sangeeta Sule and Michelle Petri",
year = "2008",
doi = "10.1016/S1571-5078(07)00219-X",
language = "English (US)",
volume = "9",
pages = "223--227",
journal = "Handbook of Systemic Autoimmune Diseases",
issn = "1571-5078",
publisher = "Elsevier BV",

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AB - There is a strong female predominance in SLE, implicating estrogens in the pathogenesis of disease. However, recent studies have shown that exogenous estrogens, given as oral contraceptives or HRT, do not increase the risk of mild or moderate flares in women with SLE. These and other studies provide physicians with new evidence for the rational use of estrogen therapy in women with SLE. {A textbox is presented}.

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