Abstract
Beta-lactam antibiotics such as cefazolin are first-line agents for preoperative prophylaxis, whereas clindamycin is often administered to patients with a reported penicillin allergy. 1 Recent studies have reported increased resistance to clindamycin in Staphylococcus aureus (SA) isolates from both pediatric and adult populations, and these changes may have implications for surgical site infection (SSI) prophylaxis and empirical management. 2 , 3 Antibiotic resistance trends of SA isolates recovered from SSIs in adults in the United States have not been recently described.
| Original language | English (US) |
|---|---|
| Journal | Infection control and hospital epidemiology |
| DOIs | |
| State | Published - Jan 1 2019 |
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ASJC Scopus subject areas
- Epidemiology
- Microbiology (medical)
- Infectious Diseases
Cite this
Changing antibiotic resistance patterns for Staphylococcus aureus surgical site infections. / Khamash, Dina F.; Milstone, Aaron; Carroll, Karen C; Gadala, Avinash; Klein, Eili; Maragakis, Lisa; Cosgrove, Sara; Fabre, Maria Valeria.
In: Infection control and hospital epidemiology, 01.01.2019.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Changing antibiotic resistance patterns for Staphylococcus aureus surgical site infections
AU - Khamash, Dina F.
AU - Milstone, Aaron
AU - Carroll, Karen C
AU - Gadala, Avinash
AU - Klein, Eili
AU - Maragakis, Lisa
AU - Cosgrove, Sara
AU - Fabre, Maria Valeria
PY - 2019/1/1
Y1 - 2019/1/1
N2 - Beta-lactam antibiotics such as cefazolin are first-line agents for preoperative prophylaxis, whereas clindamycin is often administered to patients with a reported penicillin allergy. 1 Recent studies have reported increased resistance to clindamycin in Staphylococcus aureus (SA) isolates from both pediatric and adult populations, and these changes may have implications for surgical site infection (SSI) prophylaxis and empirical management. 2 , 3 Antibiotic resistance trends of SA isolates recovered from SSIs in adults in the United States have not been recently described.
AB - Beta-lactam antibiotics such as cefazolin are first-line agents for preoperative prophylaxis, whereas clindamycin is often administered to patients with a reported penicillin allergy. 1 Recent studies have reported increased resistance to clindamycin in Staphylococcus aureus (SA) isolates from both pediatric and adult populations, and these changes may have implications for surgical site infection (SSI) prophylaxis and empirical management. 2 , 3 Antibiotic resistance trends of SA isolates recovered from SSIs in adults in the United States have not been recently described.
UR - http://www.scopus.com/inward/record.url?scp=85061936731&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=85061936731&partnerID=8YFLogxK
U2 - 10.1017/ice.2019.4
DO - 10.1017/ice.2019.4
M3 - Article
C2 - 30782221
AN - SCOPUS:85061936731
JO - Infection Control and Hospital Epidemiology
JF - Infection Control and Hospital Epidemiology
SN - 0899-823X
ER -