Changing antibiotic resistance patterns for Staphylococcus aureus surgical site infections

Dina F. Khamash; Aaron Milstone; Karen C Carroll; Avinash Gadala; Eili Klein; Lisa Maragakis; Sara Cosgrove; Maria Valeria Fabre

doi:10.1017/ice.2019.4

Changing antibiotic resistance patterns for Staphylococcus aureus surgical site infections

Dina F. Khamash, Aaron Milstone, Karen C Carroll, Avinash Gadala, Eili Klein, Lisa Maragakis, Sara Cosgrove, Maria Valeria Fabre

School of Medicine

Research output: Contribution to journal › Article › peer-review

Abstract

Beta-lactam antibiotics such as cefazolin are first-line agents for preoperative prophylaxis, whereas clindamycin is often administered to patients with a reported penicillin allergy. ¹ Recent studies have reported increased resistance to clindamycin in Staphylococcus aureus (SA) isolates from both pediatric and adult populations, and these changes may have implications for surgical site infection (SSI) prophylaxis and empirical management. ² ^, ³ Antibiotic resistance trends of SA isolates recovered from SSIs in adults in the United States have not been recently described.

Original language	English (US)
Journal	Infection control and hospital epidemiology
DOIs	https://doi.org/10.1017/ice.2019.4
State	Published - Jan 1 2019

ASJC Scopus subject areas

Epidemiology
Microbiology (medical)
Infectious Diseases

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10.1017/ice.2019.4

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title = "Changing antibiotic resistance patterns for Staphylococcus aureus surgical site infections",

abstract = " Beta-lactam antibiotics such as cefazolin are first-line agents for preoperative prophylaxis, whereas clindamycin is often administered to patients with a reported penicillin allergy. 1 Recent studies have reported increased resistance to clindamycin in Staphylococcus aureus (SA) isolates from both pediatric and adult populations, and these changes may have implications for surgical site infection (SSI) prophylaxis and empirical management. 2 , 3 Antibiotic resistance trends of SA isolates recovered from SSIs in adults in the United States have not been recently described. ",

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doi = "10.1017/ice.2019.4",

language = "English (US)",

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T1 - Changing antibiotic resistance patterns for Staphylococcus aureus surgical site infections

AU - Khamash, Dina F.

AU - Milstone, Aaron

AU - Carroll, Karen C

AU - Gadala, Avinash

AU - Klein, Eili

AU - Maragakis, Lisa

AU - Cosgrove, Sara

AU - Fabre, Maria Valeria

PY - 2019/1/1

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AB - Beta-lactam antibiotics such as cefazolin are first-line agents for preoperative prophylaxis, whereas clindamycin is often administered to patients with a reported penicillin allergy. 1 Recent studies have reported increased resistance to clindamycin in Staphylococcus aureus (SA) isolates from both pediatric and adult populations, and these changes may have implications for surgical site infection (SSI) prophylaxis and empirical management. 2 , 3 Antibiotic resistance trends of SA isolates recovered from SSIs in adults in the United States have not been recently described.

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JO - Infection Control and Hospital Epidemiology

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Changing antibiotic resistance patterns for Staphylococcus aureus surgical site infections

Abstract

ASJC Scopus subject areas

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