Changes in the concentration of breath ammonia in response to exercise: A preliminary investigation

Steven F. Solga; Matthew Mudalel; Lisa A. Spacek; Rafal Lewicki; Frank K. Tittel; Claudio Loccioni; Adolfo Russo; Alessandro Ragnoni; Terence H. Risby

doi:10.1088/1752-7155/8/3/037103

Changes in the concentration of breath ammonia in response to exercise: A preliminary investigation

Steven F. Solga, Matthew Mudalel, Lisa A. Spacek, Rafal Lewicki, Frank K. Tittel, Claudio Loccioni, Adolfo Russo, Alessandro Ragnoni, Terence H. Risby

Research output: Contribution to journal › Article › peer-review

7 Scopus citations

Abstract

Breath ammonia has proven to be a difficult compound to measure accurately. The goal of this study was to evaluate the effects that the physiological intervention, exercise, had on the levels of breath ammonia. The effects of vigorous exercise (4000 m indoor row) in 13 participants were studied and increases in breath ammonia were observed in all participants. Mean pre-exercise concentrations of ammonia were 670 pmol ml^-1CO₂(SD, 446) and these concentrations increased to post-exercise maxima of 1499 pmol ml^-1CO₂(SD, 730), p < 0.0001. The mean increase in ammonia concentrations from pre-exercise to maximum achieved in conditioned (1362 pmol ml^-1CO₂) versus non-conditioned rowers (591 pmol ml^-1CO₂) were found to be statistically different, p = 0.029. Taken together, these results demonstrate our ability to repeatedly measure the influence of exercise on the concentration of breath ammonia.

Original language	English (US)
Article number	037103
Journal	Journal of breath research
Volume	8
Issue number	3
DOIs	https://doi.org/10.1088/1752-7155/8/3/037103
State	Published - Sep 1 2014
Externally published	Yes

Keywords

ammonia production
breath ammonia
exercise
photoacoustic spectroscopy

ASJC Scopus subject areas

Pulmonary and Respiratory Medicine

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10.1088/1752-7155/8/3/037103

Cite this

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title = "Changes in the concentration of breath ammonia in response to exercise: A preliminary investigation",

abstract = "Breath ammonia has proven to be a difficult compound to measure accurately. The goal of this study was to evaluate the effects that the physiological intervention, exercise, had on the levels of breath ammonia. The effects of vigorous exercise (4000 m indoor row) in 13 participants were studied and increases in breath ammonia were observed in all participants. Mean pre-exercise concentrations of ammonia were 670 pmol ml-1CO2(SD, 446) and these concentrations increased to post-exercise maxima of 1499 pmol ml-1CO2(SD, 730), p < 0.0001. The mean increase in ammonia concentrations from pre-exercise to maximum achieved in conditioned (1362 pmol ml-1CO2) versus non-conditioned rowers (591 pmol ml-1CO2) were found to be statistically different, p = 0.029. Taken together, these results demonstrate our ability to repeatedly measure the influence of exercise on the concentration of breath ammonia.",

keywords = "ammonia production, breath ammonia, exercise, photoacoustic spectroscopy",

author = "Solga, {Steven F.} and Matthew Mudalel and Spacek, {Lisa A.} and Rafal Lewicki and Tittel, {Frank K.} and Claudio Loccioni and Adolfo Russo and Alessandro Ragnoni and Risby, {Terence H.}",

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doi = "10.1088/1752-7155/8/3/037103",

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AU - Solga, Steven F.

AU - Mudalel, Matthew

AU - Spacek, Lisa A.

AU - Lewicki, Rafal

AU - Tittel, Frank K.

AU - Loccioni, Claudio

AU - Russo, Adolfo

AU - Ragnoni, Alessandro

AU - Risby, Terence H.

PY - 2014/9/1

Y1 - 2014/9/1

N2 - Breath ammonia has proven to be a difficult compound to measure accurately. The goal of this study was to evaluate the effects that the physiological intervention, exercise, had on the levels of breath ammonia. The effects of vigorous exercise (4000 m indoor row) in 13 participants were studied and increases in breath ammonia were observed in all participants. Mean pre-exercise concentrations of ammonia were 670 pmol ml-1CO2(SD, 446) and these concentrations increased to post-exercise maxima of 1499 pmol ml-1CO2(SD, 730), p < 0.0001. The mean increase in ammonia concentrations from pre-exercise to maximum achieved in conditioned (1362 pmol ml-1CO2) versus non-conditioned rowers (591 pmol ml-1CO2) were found to be statistically different, p = 0.029. Taken together, these results demonstrate our ability to repeatedly measure the influence of exercise on the concentration of breath ammonia.

AB - Breath ammonia has proven to be a difficult compound to measure accurately. The goal of this study was to evaluate the effects that the physiological intervention, exercise, had on the levels of breath ammonia. The effects of vigorous exercise (4000 m indoor row) in 13 participants were studied and increases in breath ammonia were observed in all participants. Mean pre-exercise concentrations of ammonia were 670 pmol ml-1CO2(SD, 446) and these concentrations increased to post-exercise maxima of 1499 pmol ml-1CO2(SD, 730), p < 0.0001. The mean increase in ammonia concentrations from pre-exercise to maximum achieved in conditioned (1362 pmol ml-1CO2) versus non-conditioned rowers (591 pmol ml-1CO2) were found to be statistically different, p = 0.029. Taken together, these results demonstrate our ability to repeatedly measure the influence of exercise on the concentration of breath ammonia.

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Changes in the concentration of breath ammonia in response to exercise: A preliminary investigation

Abstract

Keywords

ASJC Scopus subject areas

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