Abstract
In our large observational cohort, use of tenofovir disoproxil fumarate (n = 344) was associated with a greater decline in renal function than was use of alternative nucleoside analogues (n = 314). Other associations included a lower CD4 cell count, decreased renal function at baseline, and diabetes. The declines were modest and did not lead to greater rates of discontinuation of therapy.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 1194-1198 |
| Number of pages | 5 |
| Journal | Clinical Infectious Diseases |
| Volume | 40 |
| Issue number | 8 |
| DOIs | |
| State | Published - Apr 15 2005 |
ASJC Scopus subject areas
- Microbiology (medical)
- Infectious Diseases
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Gallant, J. E., Parish, M. A., Keruly, J. C., & Moore, R. D. (2005). Changes in renal function associated with tenofovir disoproxil fumarate treatment, compared with nucleoside reverse-transcriptase inhibitor treatment. Clinical Infectious Diseases, 40(8), 1194-1198. https://doi.org/10.1086/428840