Changes in renal function associated with tenofovir disoproxil fumarate treatment, compared with nucleoside reverse-transcriptase inhibitor treatment

Joel E. Gallant; Michelle A. Parish; Jeanne C. Keruly; Richard D. Moore

doi:10.1086/428840

Changes in renal function associated with tenofovir disoproxil fumarate treatment, compared with nucleoside reverse-transcriptase inhibitor treatment

Joel E. Gallant, Michelle A. Parish, Jeanne C. Keruly, Richard D. Moore

School of Medicine

Research output: Contribution to journal › Article › peer-review

260 Scopus citations

Abstract

In our large observational cohort, use of tenofovir disoproxil fumarate (n = 344) was associated with a greater decline in renal function than was use of alternative nucleoside analogues (n = 314). Other associations included a lower CD4 cell count, decreased renal function at baseline, and diabetes. The declines were modest and did not lead to greater rates of discontinuation of therapy.

Original language	English (US)
Pages (from-to)	1194-1198
Number of pages	5
Journal	Clinical Infectious Diseases
Volume	40
Issue number	8
DOIs	https://doi.org/10.1086/428840
State	Published - Apr 15 2005

ASJC Scopus subject areas

Microbiology (medical)
Infectious Diseases

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10.1086/428840

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abstract = "In our large observational cohort, use of tenofovir disoproxil fumarate (n = 344) was associated with a greater decline in renal function than was use of alternative nucleoside analogues (n = 314). Other associations included a lower CD4 cell count, decreased renal function at baseline, and diabetes. The declines were modest and did not lead to greater rates of discontinuation of therapy.",

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Changes in renal function associated with tenofovir disoproxil fumarate treatment, compared with nucleoside reverse-transcriptase inhibitor treatment

Abstract

ASJC Scopus subject areas

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