Changes in renal function associated with tenofovir disoproxil fumarate treatment, compared with nucleoside reverse-transcriptase inhibitor treatment

Joel E. Gallant, Michelle A. Parish, Jeanne C. Keruly, Richard D. Moore

Research output: Contribution to journalArticle

Abstract

In our large observational cohort, use of tenofovir disoproxil fumarate (n = 344) was associated with a greater decline in renal function than was use of alternative nucleoside analogues (n = 314). Other associations included a lower CD4 cell count, decreased renal function at baseline, and diabetes. The declines were modest and did not lead to greater rates of discontinuation of therapy.

Original languageEnglish (US)
Pages (from-to)1194-1198
Number of pages5
JournalClinical Infectious Diseases
Volume40
Issue number8
DOIs
StatePublished - Apr 15 2005

ASJC Scopus subject areas

  • Microbiology (medical)
  • Infectious Diseases

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