Changes in plasma IgE levels during complicated and uncomplicated measles virus infections

Diane Griffin, Susan J. Cooper, Robert L. Hirsch, Richard Johnson, Imelda Lindo de Soriano, Susi Roedenbeck, Abraham Vaisberg

Research output: Contribution to journalArticle

Abstract

Plasma IgE levels were measured in 214 samples from 182 Peruvian patients with acute measles virus infections. Plasma IgE levels were significantly elevated early in infection compared to later time points. Plasma levels of IgG from the same patients rose during the same time period, whereas levels of IgA and IgM did not change. In patients with postmeasles encephalomyelitis, IgE remained elevated longer than it did in patients either with uncomplicated measles or measles complicated by pneumonia. It is proposed that the elevation of IgE is another manifestation of the altered immunoregulatory function in patients with measles.

Original languageEnglish (US)
Pages (from-to)206-213
Number of pages8
JournalThe Journal of Allergy and Clinical Immunology
Volume76
Issue number2 PART 1
DOIs
StatePublished - 1985

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Measles virus
Virus Diseases
Immunoglobulin E
Measles
Encephalomyelitis
Immunoglobulin A
Immunoglobulin M
Pneumonia
Immunoglobulin G
Infection

ASJC Scopus subject areas

  • Immunology
  • Immunology and Allergy

Cite this

Changes in plasma IgE levels during complicated and uncomplicated measles virus infections. / Griffin, Diane; Cooper, Susan J.; Hirsch, Robert L.; Johnson, Richard; de Soriano, Imelda Lindo; Roedenbeck, Susi; Vaisberg, Abraham.

In: The Journal of Allergy and Clinical Immunology, Vol. 76, No. 2 PART 1, 1985, p. 206-213.

Research output: Contribution to journalArticle

Griffin, Diane ; Cooper, Susan J. ; Hirsch, Robert L. ; Johnson, Richard ; de Soriano, Imelda Lindo ; Roedenbeck, Susi ; Vaisberg, Abraham. / Changes in plasma IgE levels during complicated and uncomplicated measles virus infections. In: The Journal of Allergy and Clinical Immunology. 1985 ; Vol. 76, No. 2 PART 1. pp. 206-213.
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