Changes in myocardial repolarization in patients undergoing balloon valvuloplasty for congenital pulmonary stenosis: Evidence for contraction-excitation feedback in humans

J. H. Levine, T. Guarnieri, A. H. Kadish, R. I. White, Hugh Calkins, J. S. Kan

Research output: Contribution to journalArticle

Abstract

Alterations in ventricular loading conditions lead to changes in action potential duration and arrhythmias via contraction-excitation feedback; a decrease in load leads to prolongation of repolarization. To determine whether changes in right ventricular load after ventricular repolarization in man, the corrected QT interval, a measure of overall ventricular repolarization, was measured in 32 patients before and after valvuloplasty for pulmonary stenosis. Right ventricular systolic pressure decreased (82.5 ± 30.7 to 40.5 ± 9.5 mm Hg, p

Original languageEnglish (US)
Pages (from-to)70-77
Number of pages8
JournalCirculation
Volume77
Issue number1
StatePublished - 1988

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Balloon Valvuloplasty
Pulmonary Valve Stenosis
Ventricular Pressure
Action Potentials
Cardiac Arrhythmias
Blood Pressure

ASJC Scopus subject areas

  • Physiology
  • Cardiology and Cardiovascular Medicine

Cite this

Changes in myocardial repolarization in patients undergoing balloon valvuloplasty for congenital pulmonary stenosis : Evidence for contraction-excitation feedback in humans. / Levine, J. H.; Guarnieri, T.; Kadish, A. H.; White, R. I.; Calkins, Hugh; Kan, J. S.

In: Circulation, Vol. 77, No. 1, 1988, p. 70-77.

Research output: Contribution to journalArticle

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