Changes in maternal serum thioredoxin (TRX) levels after delivery in preeclamptic and normotensive pregnant women

Nicolaos Vitoratos, Nikos F. Vlahos, Emanuel Economou, Konstatninos Panoulis, George Creatsas

    Research output: Contribution to journalArticlepeer-review

    Abstract

    Objective. To investigate changes of maternal plasma thioredoxin (TRX) levels after delivery in preeclamptic and normotensive pregnant women. Methods. Ten normotensive women (group A) were compared to 17 women with severe preeclampsia (group B). TRX levels were assessed in maternal plasma, immediately after delivery and 1216 weeks postpartum. Results. There were no differences in plasma TRX levels between the two groups immediately antepartum (p = 0.095). A significant reduction in plasma TRX levels was found immediately following delivery only in normotensive group (117.76 ± 37.19 ng/mL vs. 43.45 ± 21.11 ng/mL, p = 0.002), but not in women with preeclampsia (80.42 ± 59.95 ng/mL vs. 53.82 ± 44.34 ng/mL, p = 0.12). Plasma TRX levels remained unchanged in women with preeclampsia (80.42 ± 59.95 ng/mL vs. 55.37 ± 52.23 ng/mL, p = 0.2) at 1214 weeks postpartum.

    Original languageEnglish (US)
    Pages (from-to)140-146
    Number of pages7
    JournalHypertension in Pregnancy
    Volume31
    Issue number1
    DOIs
    StatePublished - Feb 1 2012

    Keywords

    • Antepartum
    • Postpartum
    • Preeclampsia
    • TRX

    ASJC Scopus subject areas

    • Internal Medicine
    • Obstetrics and Gynecology

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