Challenges of Conducting a Placebo-Controlled Trial for Dysmenorrhea in Adolescents

Anne R. Davis, Lauren M. Osborne, Katharine J. O'Connell, Carolyn L. Westhoff

Research output: Contribution to journalArticle

Abstract

We recruited adolescents to study oral contraceptives versus placebo for dysmenorrhea. We anticipated high discontinuation and concerns about safety, side effects, and sexual behavior. Treatment discontinuation (11%) and loss to follow-up (1%) were lower than expected. The most common reason for nonenrollment was logistical issues (63%). Most participants remained abstinent.

Original languageEnglish (US)
Pages (from-to)607-609
Number of pages3
JournalJournal of Adolescent Health
Volume39
Issue number4
DOIs
StatePublished - Oct 1 2006
Externally publishedYes

Keywords

  • Adolescents
  • Dysmenorrhea
  • Oral contraception

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health
  • Public Health, Environmental and Occupational Health
  • Psychiatry and Mental health

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