Challenges and opportunities to the design and implementation of chemoprevention trials for prostate cancer

Ian M. Thompson; Joseph A. Basler; Robin Leach; Dean Troyer; Eric Klein; Otis Brawley

doi:10.1016/S1078-1439(02)00302-2

Challenges and opportunities to the design and implementation of chemoprevention trials for prostate cancer

Ian M. Thompson, Joseph A. Basler, Robin Leach, Dean Troyer, Eric Klein, Otis Brawley

Research output: Contribution to journal › Article › peer-review

Abstract

Since 1991 and the activation of the Prostate Cancer Prevention Trial as well as similar prevention studies in several other organ sites, the interest in prostate cancer prevention has increased substantially. Despite such interest, the challenges to prevention trials-in design, implementation, prioritization, and allocation of resources-are substantial. Simultaneously, there has been an explosion in new targets and agents that may have an effect in the prevention of this disease. In this manuscript, we discuss these challenges to the study of prostate cancer prevention and provide a blueprint for prioritization of future studies.

Original language	English (US)
Pages (from-to)	73-78
Number of pages	6
Journal	Urologic Oncology: Seminars and Original Investigations
Volume	21
Issue number	1
DOIs	https://doi.org/10.1016/S1078-1439(02)00302-2
State	Published - Jan 1 2003
Externally published	Yes

ASJC Scopus subject areas

Oncology
Urology

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Challenges and opportunities to the design and implementation of chemoprevention trials for prostate cancer. / Thompson, Ian M.; Basler, Joseph A.; Leach, Robin; Troyer, Dean; Klein, Eric; Brawley, Otis.

In: Urologic Oncology: Seminars and Original Investigations, Vol. 21, No. 1, 01.01.2003, p. 73-78.

Research output: Contribution to journal › Article › peer-review

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