CEST MRI reporter genes

Guanshu Liu, Jeff W.M. Bulte, Assaf A. Gilad

Research output: Chapter in Book/Report/Conference proceedingChapter

Abstract

In recent years, several reporter genes have been developed that can serve as a beacon for non-invasive magnetic resonance imaging (MRI). Here, we provide a brief summary of recent advances in MRI reporter gene technology, as well as detailed "hands-on" protocols for cloning, expression, and imaging of reporter genes based on chemical exchange saturation transfer (CEST).

Original languageEnglish (US)
Title of host publicationMagnetic Resonance Neuroimaging
Subtitle of host publicationMethods and Protocols
EditorsMichel Modo, Jelte Bulte
Pages271-280
Number of pages10
DOIs
StatePublished - Dec 1 2010

Publication series

NameMethods in Molecular Biology
Volume711
ISSN (Print)1064-3745

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Keywords

  • Chemical exchange saturation transfer
  • cell tracking
  • cloning
  • expression vector
  • molecular imaging
  • reporter gene

ASJC Scopus subject areas

  • Molecular Biology
  • Genetics

Cite this

Liu, G., Bulte, J. W. M., & Gilad, A. A. (2010). CEST MRI reporter genes. In M. Modo, & J. Bulte (Eds.), Magnetic Resonance Neuroimaging: Methods and Protocols (pp. 271-280). (Methods in Molecular Biology; Vol. 711). https://doi.org/10.1007/978-1-61737-992-5_13