Cervical ectopy and the transformation zone measured by computerized planimetry in adolescents

D. L. Jacobson, L. Peralta, M. Farmer, N. M H Graham, T. C. Wright, Jonathan Mark Zenilman

Research output: Contribution to journalArticle

Abstract

Objective: To determine whether cervical ectopy and the transformation (T) zone were larger in adolescents using oral contraceptives (OCs) compared to depot medroxyprogesterone acetate (DMPA). Method: Cervical photographs were taken on 91 adolescents in Baltimore, Maryland. Ectopy and T zone size were measured using computerized planimetry. Patients provided reproductive and sexual history. Correlates of ectopy and T zone size were identified by proportional odds and linear regression models, respectively. Result: Twenty-five women had no ectopy. Parity was independently associated with greater ectopy (OR 3.9, 95% CI 1.37-11.11). Predictors of smaller ectopy were douching (OR 0.23, 95% CI 0.09-0.65), and shorter sexual history (OR 0.20, 95% CI 0.05-0.74). Neither OC or DMPA were associated with ectopy. Predictors of greater T zone size were years since menarche (13.8 mm2/year, P=0.003) and OCs (54.7 mm2, P=0.05). DMPA predicted a smaller T zone (-67.0 mm2, P=0.01). Conclusion: Computerized planimetry provides standardized measurements. Douching and sexual activity may decrease ectopy through increased squamous metaplasia. Hormonal contraceptives were not associated with ectopy in adolescents. However, long-term progestin use may decrease T zone size. Copyright (C) 1999 International Federation of Gynceology and Obstetrics.

Original languageEnglish (US)
Pages (from-to)7-17
Number of pages11
JournalInternational Journal of Gynecology and Obstetrics
Volume66
Issue number1
DOIs
StatePublished - Jul 1 1999

Fingerprint

Medroxyprogesterone Acetate
Oral Contraceptives
Therapeutic Irrigation
Linear Models
Reproductive History
Baltimore
Menarche
Metaplasia
Progestins
Contraceptive Agents
Parity
Sexual Behavior
Obstetrics

Keywords

  • Adolescents
  • Cervical ectopy
  • Computerized planimetry
  • Depot medroxyprogesterone acetate
  • DMPA
  • Oral contraceptives
  • Transformation zone

ASJC Scopus subject areas

  • Obstetrics and Gynecology

Cite this

Cervical ectopy and the transformation zone measured by computerized planimetry in adolescents. / Jacobson, D. L.; Peralta, L.; Farmer, M.; Graham, N. M H; Wright, T. C.; Zenilman, Jonathan Mark.

In: International Journal of Gynecology and Obstetrics, Vol. 66, No. 1, 01.07.1999, p. 7-17.

Research output: Contribution to journalArticle

Jacobson, D. L. ; Peralta, L. ; Farmer, M. ; Graham, N. M H ; Wright, T. C. ; Zenilman, Jonathan Mark. / Cervical ectopy and the transformation zone measured by computerized planimetry in adolescents. In: International Journal of Gynecology and Obstetrics. 1999 ; Vol. 66, No. 1. pp. 7-17.
@article{9e9aad8d64af4e24a1fdf3ddf41c4c6e,
title = "Cervical ectopy and the transformation zone measured by computerized planimetry in adolescents",
abstract = "Objective: To determine whether cervical ectopy and the transformation (T) zone were larger in adolescents using oral contraceptives (OCs) compared to depot medroxyprogesterone acetate (DMPA). Method: Cervical photographs were taken on 91 adolescents in Baltimore, Maryland. Ectopy and T zone size were measured using computerized planimetry. Patients provided reproductive and sexual history. Correlates of ectopy and T zone size were identified by proportional odds and linear regression models, respectively. Result: Twenty-five women had no ectopy. Parity was independently associated with greater ectopy (OR 3.9, 95{\%} CI 1.37-11.11). Predictors of smaller ectopy were douching (OR 0.23, 95{\%} CI 0.09-0.65), and shorter sexual history (OR 0.20, 95{\%} CI 0.05-0.74). Neither OC or DMPA were associated with ectopy. Predictors of greater T zone size were years since menarche (13.8 mm2/year, P=0.003) and OCs (54.7 mm2, P=0.05). DMPA predicted a smaller T zone (-67.0 mm2, P=0.01). Conclusion: Computerized planimetry provides standardized measurements. Douching and sexual activity may decrease ectopy through increased squamous metaplasia. Hormonal contraceptives were not associated with ectopy in adolescents. However, long-term progestin use may decrease T zone size. Copyright (C) 1999 International Federation of Gynceology and Obstetrics.",
keywords = "Adolescents, Cervical ectopy, Computerized planimetry, Depot medroxyprogesterone acetate, DMPA, Oral contraceptives, Transformation zone",
author = "Jacobson, {D. L.} and L. Peralta and M. Farmer and Graham, {N. M H} and Wright, {T. C.} and Zenilman, {Jonathan Mark}",
year = "1999",
month = "7",
day = "1",
doi = "10.1016/S0020-7292(99)00037-5",
language = "English (US)",
volume = "66",
pages = "7--17",
journal = "International Journal of Gynecology and Obstetrics",
issn = "0020-7292",
publisher = "Elsevier Ireland Ltd",
number = "1",

}

TY - JOUR

T1 - Cervical ectopy and the transformation zone measured by computerized planimetry in adolescents

AU - Jacobson, D. L.

AU - Peralta, L.

AU - Farmer, M.

AU - Graham, N. M H

AU - Wright, T. C.

AU - Zenilman, Jonathan Mark

PY - 1999/7/1

Y1 - 1999/7/1

N2 - Objective: To determine whether cervical ectopy and the transformation (T) zone were larger in adolescents using oral contraceptives (OCs) compared to depot medroxyprogesterone acetate (DMPA). Method: Cervical photographs were taken on 91 adolescents in Baltimore, Maryland. Ectopy and T zone size were measured using computerized planimetry. Patients provided reproductive and sexual history. Correlates of ectopy and T zone size were identified by proportional odds and linear regression models, respectively. Result: Twenty-five women had no ectopy. Parity was independently associated with greater ectopy (OR 3.9, 95% CI 1.37-11.11). Predictors of smaller ectopy were douching (OR 0.23, 95% CI 0.09-0.65), and shorter sexual history (OR 0.20, 95% CI 0.05-0.74). Neither OC or DMPA were associated with ectopy. Predictors of greater T zone size were years since menarche (13.8 mm2/year, P=0.003) and OCs (54.7 mm2, P=0.05). DMPA predicted a smaller T zone (-67.0 mm2, P=0.01). Conclusion: Computerized planimetry provides standardized measurements. Douching and sexual activity may decrease ectopy through increased squamous metaplasia. Hormonal contraceptives were not associated with ectopy in adolescents. However, long-term progestin use may decrease T zone size. Copyright (C) 1999 International Federation of Gynceology and Obstetrics.

AB - Objective: To determine whether cervical ectopy and the transformation (T) zone were larger in adolescents using oral contraceptives (OCs) compared to depot medroxyprogesterone acetate (DMPA). Method: Cervical photographs were taken on 91 adolescents in Baltimore, Maryland. Ectopy and T zone size were measured using computerized planimetry. Patients provided reproductive and sexual history. Correlates of ectopy and T zone size were identified by proportional odds and linear regression models, respectively. Result: Twenty-five women had no ectopy. Parity was independently associated with greater ectopy (OR 3.9, 95% CI 1.37-11.11). Predictors of smaller ectopy were douching (OR 0.23, 95% CI 0.09-0.65), and shorter sexual history (OR 0.20, 95% CI 0.05-0.74). Neither OC or DMPA were associated with ectopy. Predictors of greater T zone size were years since menarche (13.8 mm2/year, P=0.003) and OCs (54.7 mm2, P=0.05). DMPA predicted a smaller T zone (-67.0 mm2, P=0.01). Conclusion: Computerized planimetry provides standardized measurements. Douching and sexual activity may decrease ectopy through increased squamous metaplasia. Hormonal contraceptives were not associated with ectopy in adolescents. However, long-term progestin use may decrease T zone size. Copyright (C) 1999 International Federation of Gynceology and Obstetrics.

KW - Adolescents

KW - Cervical ectopy

KW - Computerized planimetry

KW - Depot medroxyprogesterone acetate

KW - DMPA

KW - Oral contraceptives

KW - Transformation zone

UR - http://www.scopus.com/inward/record.url?scp=0032995008&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0032995008&partnerID=8YFLogxK

U2 - 10.1016/S0020-7292(99)00037-5

DO - 10.1016/S0020-7292(99)00037-5

M3 - Article

C2 - 10458544

AN - SCOPUS:0032995008

VL - 66

SP - 7

EP - 17

JO - International Journal of Gynecology and Obstetrics

JF - International Journal of Gynecology and Obstetrics

SN - 0020-7292

IS - 1

ER -