Cervical ectopy and the transformation zone measured by computerized planimetry in adolescents

D. L. Jacobson, L. Peralta, M. Farmer, N. M.H. Graham, T. C. Wright, J. Zenilman

Research output: Contribution to journalArticle

Abstract

Objective: To determine whether cervical ectopy and the transformation (T) zone were larger in adolescents using oral contraceptives (OCs) compared to depot medroxyprogesterone acetate (DMPA). Method: Cervical photographs were taken on 91 adolescents in Baltimore, Maryland. Ectopy and T zone size were measured using computerized planimetry. Patients provided reproductive and sexual history. Correlates of ectopy and T zone size were identified by proportional odds and linear regression models, respectively. Result: Twenty-five women had no ectopy. Parity was independently associated with greater ectopy (OR 3.9, 95% CI 1.37-11.11). Predictors of smaller ectopy were douching (OR 0.23, 95% CI 0.09-0.65), and shorter sexual history (OR 0.20, 95% CI 0.05-0.74). Neither OC or DMPA were associated with ectopy. Predictors of greater T zone size were years since menarche (13.8 mm2/year, P=0.003) and OCs (54.7 mm2, P=0.05). DMPA predicted a smaller T zone (-67.0 mm2, P=0.01). Conclusion: Computerized planimetry provides standardized measurements. Douching and sexual activity may decrease ectopy through increased squamous metaplasia. Hormonal contraceptives were not associated with ectopy in adolescents. However, long-term progestin use may decrease T zone size. Copyright (C) 1999 International Federation of Gynceology and Obstetrics.

Original languageEnglish (US)
Pages (from-to)7-17
Number of pages11
JournalInternational Journal of Gynecology and Obstetrics
Volume66
Issue number1
DOIs
StatePublished - Jul 1 1999

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Keywords

  • Adolescents
  • Cervical ectopy
  • Computerized planimetry
  • DMPA
  • Depot medroxyprogesterone acetate
  • Oral contraceptives
  • Transformation zone

ASJC Scopus subject areas

  • Obstetrics and Gynecology

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