Cervical ectopic pregnancy: Review of the literature and report of a case treated by single-dose methotrexate therapy

Jerome Yankowitz, Jonathan Leake, George Huggins, Preston Gazaway, Elena Gates

Research output: Contribution to journalReview article


Methotrexate with folinic acid rescue was used to terminate a clinically diagnosed cervical pregnancy while preserving reproductive capability in a young female patient.The chemotherapy was well tolerated except for transient elevation of liver enzymes. Beta HCG titers fell rapidly and became negative by 13 days. This is the first report showing successful treatment of a cervical pregnancy with single-dose chemotherapy. The literature is reviewed and discussed.

Original languageEnglish (US)
Pages (from-to)405-414
Number of pages10
JournalObstetrical and Gynecological Survey
Issue number7
StatePublished - Jul 1990


ASJC Scopus subject areas

  • Obstetrics and Gynecology

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