Cervical dysplasia in pregnancy: A multi-institutional evaluation

Amanda N. Fader, Erin K. Alward, Amy Niederhauser, Christina Chirico, Jamie L. Lesnock, Daniel J. Zwiesler, Richard S. Guido, Darla J. Lofgren, Michael A. Gold, Kathleen N. Moore

Research output: Contribution to journalArticlepeer-review


Objective: This study was undertaken to identify the prognostic indicators associated with postpartum regression of cervical dysplasia diagnosed in pregnancy. Study Design: A retrospective cohort study of pregnant women referred for colposcopy from 2004-2007 at four academic centers. Results: One thousand seventy-nine patients were identified. Colposcopic impression by cervical cytology is detailed later in the text. Of patients who underwent biopsy, results correlated with or were less severe than colposcopic impression in 83% with CIN 1 and 56% with CIN 2/3. Fifty-seven percent had follow-up postpartum, with 61% reverting to normal. Resolution of cervical dysplasia was inversely associated with smoking (P = .002). No progression to cancer occurred during pregnancy. Conclusion: Colposcopic impression in pregnancy correlated with cervical biopsy results and postpartum colposcopic findings when performed by expert colposcopists. A high proportion of cervical dysplasia regressed postpartum. Cervical biopsies in pregnancy may not be necessary unless invasive cancer is suspected.

Original languageEnglish (US)
Pages (from-to)113.e1-113.e6
JournalAmerican journal of obstetrics and gynecology
Issue number2
StatePublished - 2010


  • HSIL
  • cervical dysplasia
  • colposcopy
  • pregnancy

ASJC Scopus subject areas

  • Obstetrics and Gynecology


Dive into the research topics of 'Cervical dysplasia in pregnancy: A multi-institutional evaluation'. Together they form a unique fingerprint.

Cite this