Cerebrovascular risk factors and depression in older primary care patients

J. M. Lyness, E. D. Caine, D. A. King, Y. Conwell, Christopher Cox, P. R. Duberstein

Research output: Contribution to journalArticle

Abstract

The authors examined whether cerebrovascular risk factors (CVRFs) are associated with depressive diagnoses and symptoms in 303 primary-care patients age ≥60 years, as would be consistent with a small-vessel brain disease model of later-life depression. CVRFs were not significantly independently associated with major, minor, or subsyndromal depression, late- onset major depression, or overall depressive symptom severity. These data did not support the notion that a small-vessel brain disease model of depression might apply to the majority of older persons with depressive symptoms and syndromes in primary-care settings. Future work should include longitudinal study with larger sample sizes.

Original languageEnglish (US)
Pages (from-to)252-258
Number of pages7
JournalAmerican Journal of Geriatric Psychiatry
Volume7
Issue number3
DOIs
StatePublished - 1999
Externally publishedYes

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Primary Health Care
Depression
Brain Diseases
Depressive Disorder
Sample Size
Longitudinal Studies

ASJC Scopus subject areas

  • Psychiatry and Mental health
  • Geriatrics and Gerontology

Cite this

Cerebrovascular risk factors and depression in older primary care patients. / Lyness, J. M.; Caine, E. D.; King, D. A.; Conwell, Y.; Cox, Christopher; Duberstein, P. R.

In: American Journal of Geriatric Psychiatry, Vol. 7, No. 3, 1999, p. 252-258.

Research output: Contribution to journalArticle

Lyness, J. M. ; Caine, E. D. ; King, D. A. ; Conwell, Y. ; Cox, Christopher ; Duberstein, P. R. / Cerebrovascular risk factors and depression in older primary care patients. In: American Journal of Geriatric Psychiatry. 1999 ; Vol. 7, No. 3. pp. 252-258.
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