Abstract
The authors examined whether cerebrovascular risk factors (CVRFs) are associated with depressive diagnoses and symptoms in 303 primary-care patients age ≥60 years, as would be consistent with a small-vessel brain disease model of later-life depression. CVRFs were not significantly independently associated with major, minor, or subsyndromal depression, late-onset major depression, or overall depressive symptom severity. These data did not support the notion that a small-vessel brain disease model of depression might apply to the majority of older persons with depressive symptoms and syndromes in primary-care settings. Future work should include longitudinal study with larger sample sizes.
Original language | English (US) |
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Pages (from-to) | 252-258 |
Number of pages | 7 |
Journal | American Journal of Geriatric Psychiatry |
Volume | 7 |
Issue number | 3 |
DOIs | |
State | Published - 1999 |
Externally published | Yes |
ASJC Scopus subject areas
- Geriatrics and Gerontology
- Psychiatry and Mental health