Cerebrovascular disease basis of depression: Post-stroke depression and vascular depression

Andrew R. Newberg, Dimitry S. Davydow, Hochang B. Lee

Research output: Contribution to journalArticlepeer-review


The close association between cerebrovascular disease and depression has been known for more than a century, yet much of the progress in understanding the cerebrovascular basis of depression in late life has been spurred by development of two concepts: 'post-stroke depression' and 'vascular depression'. The purpose of this review is to examine the epidemiology, diagnostic features, course, pathophysiology and prognosis of post-stroke depression and vascular depression, to highlight their common features, and to contrast the distinct aspects of these two subtypes of geriatric depression.

Original languageEnglish (US)
Pages (from-to)433-441
Number of pages9
JournalInternational Review of Psychiatry
Issue number5
StatePublished - Oct 1 2006

ASJC Scopus subject areas

  • Psychiatry and Mental health


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