Abstract
Because of observed cerebral blood flow changes in hydroceplialus, we hypothesised that there is a preferential compression of the cerebral vessels accompanying chronic tissue compression. In this preliminary study we quantitated 12 animals that underwent successful surgical induction of hydrocephalus via cyanoacrylic glue injection into the IVth ventricle. We investigated the degree and pattern of vascular compression by measuring the vessel density, diameter, and area percent in three serial sections from multiple regions m the parieto-occipital lobe. These parameters were related to the degree of tissue compression, as measured by post-induction .MR1. An overall increase in blood vessel area was observed in periventricular white matter (PW) (p = 0.036) and in superficial grey matter (p = 0.020). Vessel diameters were increased overall (p
| Original language | English (US) |
|---|---|
| Pages (from-to) | 53 |
| Number of pages | 1 |
| Journal | European Journal of Pediatric Surgery, Supplement |
| Volume | 9 |
| Issue number | 1 |
| State | Published - 1999 |
| Externally published | Yes |
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ASJC Scopus subject areas
- Pediatrics, Perinatology, and Child Health
Cite this
Cerebrovascular compression in a canine model of obstructive hydrocephalus. / Luciano, Mark; Skarupa, D. J.; Booth, A. M.; Johnson, M. J.; Ayznian, I.; Wood, A. S.; Hoegler, J. J.
In: European Journal of Pediatric Surgery, Supplement, Vol. 9, No. 1, 1999, p. 53.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Cerebrovascular compression in a canine model of obstructive hydrocephalus
AU - Luciano, Mark
AU - Skarupa, D. J.
AU - Booth, A. M.
AU - Johnson, M. J.
AU - Ayznian, I.
AU - Wood, A. S.
AU - Hoegler, J. J.
PY - 1999
Y1 - 1999
N2 - Because of observed cerebral blood flow changes in hydroceplialus, we hypothesised that there is a preferential compression of the cerebral vessels accompanying chronic tissue compression. In this preliminary study we quantitated 12 animals that underwent successful surgical induction of hydrocephalus via cyanoacrylic glue injection into the IVth ventricle. We investigated the degree and pattern of vascular compression by measuring the vessel density, diameter, and area percent in three serial sections from multiple regions m the parieto-occipital lobe. These parameters were related to the degree of tissue compression, as measured by post-induction .MR1. An overall increase in blood vessel area was observed in periventricular white matter (PW) (p = 0.036) and in superficial grey matter (p = 0.020). Vessel diameters were increased overall (p
AB - Because of observed cerebral blood flow changes in hydroceplialus, we hypothesised that there is a preferential compression of the cerebral vessels accompanying chronic tissue compression. In this preliminary study we quantitated 12 animals that underwent successful surgical induction of hydrocephalus via cyanoacrylic glue injection into the IVth ventricle. We investigated the degree and pattern of vascular compression by measuring the vessel density, diameter, and area percent in three serial sections from multiple regions m the parieto-occipital lobe. These parameters were related to the degree of tissue compression, as measured by post-induction .MR1. An overall increase in blood vessel area was observed in periventricular white matter (PW) (p = 0.036) and in superficial grey matter (p = 0.020). Vessel diameters were increased overall (p
UR - http://www.scopus.com/inward/record.url?scp=33748175564&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=33748175564&partnerID=8YFLogxK
M3 - Article
VL - 9
SP - 53
JO - European Journal of Pediatric Surgery, Supplement
JF - European Journal of Pediatric Surgery, Supplement
SN - 0939-6764
IS - 1
ER -