Abstract
We measured CSF levels of homovanillic acid (HVA) and 5-hydroxyindoleacetic acid (5-HIAA) by high-performance liquid chromatography in seven children with infantile spasms and in a group of ageand sex-matched controls. The mean concentration of the serotonin metabolite 5-HIAA was 40% (p < 0.01) lower in the infantile spasms group as compared with controls; HVA levels were similar in both groups. The data provide additional evidence that serotonin metabolism is abnormal in patients with infantile spasms.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 102-105 |
| Number of pages | 4 |
| Journal | Neurology |
| Volume | 34 |
| Issue number | 1 |
| DOIs | |
| State | Published - Jan 1984 |
| Externally published | Yes |
ASJC Scopus subject areas
- Clinical Neurology