CEREBROSPINAL-FLUID LYMPHOCYTE POPULATIONS AND IMMUNE COMPLEXES IN ACTIVE MULTIPLE SCLEROSIS

P. K. Coyle, Robert L. Hirsch, Patricia O'Donnell, Benjamin R. Brooks, Steven R. Cohen, Richard T. Johnson, Jerry S. Wolinsky

Research output: Contribution to journalArticlepeer-review

Abstract

A specific subpopulation of mononuclear cells bearing a surface receptor for the Fc portion of IgG was considerably reduced in the cerebrospinal fluid (CSF) of multiple sclerosis (MS) patients during exacerbation, but returned toward normal levels as the patient entered remission. Low concentrations of immune complexes were found in the CSF in nearly 50% of MS patients during exacerbations but immune complexes were not found in patients with stable MS.

Original languageEnglish (US)
Pages (from-to)229-232
Number of pages4
JournalThe Lancet
Volume316
Issue number8188
DOIs
StatePublished - 1980

ASJC Scopus subject areas

  • Medicine(all)

Fingerprint

Dive into the research topics of 'CEREBROSPINAL-FLUID LYMPHOCYTE POPULATIONS AND IMMUNE COMPLEXES IN ACTIVE MULTIPLE SCLEROSIS'. Together they form a unique fingerprint.

Cite this