Cerebral ventricular enlargement in schizophreniform disorder does not progress A seven year follow-up study

George E. Jaskiw, Denise M. Juliano, Terence E. Goldberg, Marc Hertzman, Edward Urow-Hamell, Daniel R. Weinberger

Research output: Contribution to journalArticle

Abstract

Ten patients, who underwent computerized tomography (CT) study during evaluation for first episode schizophreniform psychosis were restudied an average of 7 years later. Of the 10 patients, 7 were found to carry a diagnosis of schizophrenia at follow-up. In this subgroup, there was no significant change in the mean ventricular brain ratio measure of cerebral ventricular size between the index and follow-up scans. These findings are consistent with the hypothesis that ventricular enlargement is present at the onset of schizophrenia and does not progress with duration of illness or treatment.

Original languageEnglish (US)
Pages (from-to)23-28
Number of pages6
JournalSchizophrenia Research
Volume14
Issue number1
DOIs
StatePublished - Dec 1994
Externally publishedYes

Keywords

  • Chronic schizophrenia
  • Computerized tomography
  • Schizophreniform
  • Ventricular brain ratio

ASJC Scopus subject areas

  • Psychiatry and Mental health
  • Biological Psychiatry

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