Cerebral vasculopathy associated with collateralization resembling moya moya phenomenon and with anti‐Ro/SS‐A and anti–La/SS‐B antibodies

Thomas T. Provost, Howard Moses, E. Morris, Jeremy Altman, John B. Harley, Elaine Alexander, Morris Reichlin

Research output: Contribution to journalArticle

Abstract

We describe a 48‐year‐old, previously healthy, anti–Ro/SS‐A and anti–La/SS‐B antibody positive black woman with negative risk factors for atherosclerosis, who developed mental status and personality changes over a 6–12‐month period, and progressive cortical blindness over a 2‐week period. Angiographic and computed axial tomographic studies of the brain demonstrated multiple large areas of infarction correlating with stenosis and occlusions of the internal carotid and posterior cerebral arteries. Moya moya–like findings were prominent radiographically. Results of angiographic, computed tomographic, and magnetic resonance imaging studies were interpreted as being compatible with large, medium, and small vessel disease, most likely a vasculitis.

Original languageEnglish (US)
Pages (from-to)1052-1055
Number of pages4
JournalArthritis & Rheumatism
Volume34
Issue number8
DOIs
StatePublished - Jan 1 1991

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Cortical Blindness
Posterior Cerebral Artery
Vasculitis
Infarction
Personality
Atherosclerosis
Pathologic Constriction
Magnetic Resonance Imaging
Antibodies
Brain

ASJC Scopus subject areas

  • Immunology and Allergy
  • Rheumatology
  • Immunology
  • Pharmacology (medical)

Cite this

Cerebral vasculopathy associated with collateralization resembling moya moya phenomenon and with anti‐Ro/SS‐A and anti–La/SS‐B antibodies. / Provost, Thomas T.; Moses, Howard; Morris, E.; Altman, Jeremy; Harley, John B.; Alexander, Elaine; Reichlin, Morris.

In: Arthritis & Rheumatism, Vol. 34, No. 8, 01.01.1991, p. 1052-1055.

Research output: Contribution to journalArticle

Provost, Thomas T. ; Moses, Howard ; Morris, E. ; Altman, Jeremy ; Harley, John B. ; Alexander, Elaine ; Reichlin, Morris. / Cerebral vasculopathy associated with collateralization resembling moya moya phenomenon and with anti‐Ro/SS‐A and anti–La/SS‐B antibodies. In: Arthritis & Rheumatism. 1991 ; Vol. 34, No. 8. pp. 1052-1055.
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