Cerebral thrombosis associated with active Crohn's disease.

R. Calderón, M. R. Cruz-Correa, E. A. Torres

Research output: Contribution to journalArticle

Abstract

An increased incidence of cerebral thromboembolic events has been reported in young patients with inflammatory bowel disease (IBD). It has been suggested that a hypercoagulable state is associated with clinical activity of the disease, with elevation of factors V, VIII, fibrinogen and platelets and a lowering of anti-thrombin III. We present the case of a 35 y/o male with refractory Crohn's disease who complained of headaches, blurred vision and tonic-clonic seizures. The studies demonstrated an ischemic stroke of the left cerebral hemisphere, without vascular abnormalities. Elevation of factor VIII, platelets, and antithrombin III were found. The symptoms were relieved with medical treatment and the patient has continued in good health after resection of the diseased terminal ileum.

Original languageEnglish (US)
Pages (from-to)293-295
Number of pages3
JournalPuerto Rico Health Sciences Journal
Volume17
Issue number3
StatePublished - 1998
Externally publishedYes

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Intracranial Thrombosis
Factor VIII
Crohn Disease
Blood Platelets
Factor V
Antithrombin III
Cerebrum
Ileum
Inflammatory Bowel Diseases
Thrombin
Fibrinogen
Blood Vessels
Headache
Seizures
Stroke
Incidence
Health
Therapeutics

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Calderón, R., Cruz-Correa, M. R., & Torres, E. A. (1998). Cerebral thrombosis associated with active Crohn's disease. Puerto Rico Health Sciences Journal, 17(3), 293-295.

Cerebral thrombosis associated with active Crohn's disease. / Calderón, R.; Cruz-Correa, M. R.; Torres, E. A.

In: Puerto Rico Health Sciences Journal, Vol. 17, No. 3, 1998, p. 293-295.

Research output: Contribution to journalArticle

Calderón, R, Cruz-Correa, MR & Torres, EA 1998, 'Cerebral thrombosis associated with active Crohn's disease.', Puerto Rico Health Sciences Journal, vol. 17, no. 3, pp. 293-295.
Calderón, R. ; Cruz-Correa, M. R. ; Torres, E. A. / Cerebral thrombosis associated with active Crohn's disease. In: Puerto Rico Health Sciences Journal. 1998 ; Vol. 17, No. 3. pp. 293-295.
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