TY - JOUR
T1 - Cerebral palsy and developmental intellectual disability in children younger than 5 years
T2 - Findings from the GBD-WHO Rehabilitation Database 2019
AU - Global Research on Developmental Disabilities Collaborators (GRDDC)
AU - Olusanya, Bolajoko O.
AU - Gladstone, Melissa
AU - Wright, Scott M.
AU - Hadders-Algra, Mijna
AU - Boo, Nem Yun
AU - Nair, M. K.C.
AU - Almasri, Nihad
AU - Kancherla, Vijaya
AU - Samms-Vaughan, Maureen E.
AU - Kakooza-Mwesige, Angelina
AU - Smythe, Tracey
AU - del Castillo-Hegyi, Christie
AU - Halpern, Ricardo
AU - de Camargo, Olaf K.
AU - Arabloo, Jalal
AU - Eftekhari, Aziz
AU - Shaheen, Amira
AU - Gulati, Sheffali
AU - Williams, Andrew N.
AU - Olusanya, Jacob O.
AU - Wertlieb, Donald
AU - Newton, Charles R.J.
AU - Davis, Adrian C.
N1 - Publisher Copyright:
Copyright © 2022 Olusanya, Gladstone, Wright, Hadders-Algra, Boo, Nair, Almasri, Kancherla, Samms-Vaughan, Kakooza-Mwesige, Smythe, del Castillo-Hegyi, Halpern, de Camargo, Arabloo, Eftekhari, Shaheen, Gulati, Williams, Olusanya, Wertlieb, Newton and Davis.
PY - 2022/8/25
Y1 - 2022/8/25
N2 - Objective: Children with developmental disabilities are associated with a high risk of poor school enrollment and educational attainment without timely and appropriate support. Epidemiological data on cerebral palsy and associated comorbidities required for policy intervention in global health are lacking. This paper set out to report the best available evidence on the global and regional prevalence of cerebral palsy (CP) and developmental intellectual disability and the associated “years lived with disability” (YLDs) among children under 5 years of age in 2019. Methods: We analyzed the collaborative 2019 Rehabilitation Database of the Global Burden of Disease (GBD) Study and World Health Organization for neurological and mental disorders available for 204 countries and territories. Point prevalence and YLDs with 95% uncertainty intervals (UI) are presented. Results: Globally, 8.1 million (7.1–9.2) or 1.2% of children under 5 years are estimated to have CP with 16.1 million (11.5–21.0) or 2.4% having intellectual disability. Over 98% resided in low-income and middle-income countries (LMICs). CP and intellectual disability accounted for 6.5% and 4.5% of the aggregate YLDs from all causes of adverse health outcomes respectively. African Region recorded the highest prevalence of CP (1.6%) while South-East Asia Region had the highest prevalence of intellectual disability. The top 10 countries accounted for 57.2% of the global prevalence of CP and 62.0% of the global prevalence of intellectual disability. Conclusion: Based on this Database, CP and intellectual disability are highly prevalent and associated with substantial YLDs among children under 5 years worldwide. Universal early detection and support services are warranted, particularly in LMICs to optimize school readiness for these children toward inclusive education as envisioned by the United Nations' Sustainable Development Goals.
AB - Objective: Children with developmental disabilities are associated with a high risk of poor school enrollment and educational attainment without timely and appropriate support. Epidemiological data on cerebral palsy and associated comorbidities required for policy intervention in global health are lacking. This paper set out to report the best available evidence on the global and regional prevalence of cerebral palsy (CP) and developmental intellectual disability and the associated “years lived with disability” (YLDs) among children under 5 years of age in 2019. Methods: We analyzed the collaborative 2019 Rehabilitation Database of the Global Burden of Disease (GBD) Study and World Health Organization for neurological and mental disorders available for 204 countries and territories. Point prevalence and YLDs with 95% uncertainty intervals (UI) are presented. Results: Globally, 8.1 million (7.1–9.2) or 1.2% of children under 5 years are estimated to have CP with 16.1 million (11.5–21.0) or 2.4% having intellectual disability. Over 98% resided in low-income and middle-income countries (LMICs). CP and intellectual disability accounted for 6.5% and 4.5% of the aggregate YLDs from all causes of adverse health outcomes respectively. African Region recorded the highest prevalence of CP (1.6%) while South-East Asia Region had the highest prevalence of intellectual disability. The top 10 countries accounted for 57.2% of the global prevalence of CP and 62.0% of the global prevalence of intellectual disability. Conclusion: Based on this Database, CP and intellectual disability are highly prevalent and associated with substantial YLDs among children under 5 years worldwide. Universal early detection and support services are warranted, particularly in LMICs to optimize school readiness for these children toward inclusive education as envisioned by the United Nations' Sustainable Development Goals.
KW - SDGs
KW - cerebral palsy
KW - developmental disabilities
KW - early intervention
KW - global burden of disease
KW - global health
KW - intellectual disability
KW - rehabilitation
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UR - http://www.scopus.com/inward/citedby.url?scp=85137703266&partnerID=8YFLogxK
U2 - 10.3389/fpubh.2022.894546
DO - 10.3389/fpubh.2022.894546
M3 - Article
C2 - 36091559
AN - SCOPUS:85137703266
SN - 2296-2565
VL - 10
JO - Frontiers in Public Health
JF - Frontiers in Public Health
M1 - 894546
ER -