Cerebral energy metabolism in rats studied by phosphorus nuclear magnetic resonance using surface coils

Paul A. Bottomley; Kyuya Kogure; Richard Namon; Ofelia F. Alonso

doi:10.1016/0730-725X(82)90223-5

Cerebral energy metabolism in rats studied by phosphorus nuclear magnetic resonance using surface coils

Paul A. Bottomley, Kyuya Kogure, Richard Namon, Ofelia F. Alonso

School of Medicine

Research output: Contribution to journal › Article › peer-review

Abstract

Phosphorus nuclear magnetic resonance with surface coils was used to investigate the regional metabolism of the rat brain in vivo under conditions of normoxia, severe hypoxemia, partial necrosis, and partial ischemia. The results show an increase in sugar phosphate and/or inorganic phosphate with injury in accordance with in vivo assays. The technique provides a powerful means of monitoring the metabolism of stroke and its response to therapy in vivo.

Original language	English (US)
Pages (from-to)	81-85
Number of pages	5
Journal	Magnetic Resonance Imaging
Volume	1
Issue number	2
DOIs	https://doi.org/10.1016/0730-725X(82)90223-5
State	Published - 1982

Keywords

Energy metabolism
Nuclear magnetic resonance
Phosphorus
Surface coils

ASJC Scopus subject areas

Biophysics
Biomedical Engineering
Radiology Nuclear Medicine and imaging

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10.1016/0730-725X(82)90223-5

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title = "Cerebral energy metabolism in rats studied by phosphorus nuclear magnetic resonance using surface coils",

abstract = "Phosphorus nuclear magnetic resonance with surface coils was used to investigate the regional metabolism of the rat brain in vivo under conditions of normoxia, severe hypoxemia, partial necrosis, and partial ischemia. The results show an increase in sugar phosphate and/or inorganic phosphate with injury in accordance with in vivo assays. The technique provides a powerful means of monitoring the metabolism of stroke and its response to therapy in vivo.",

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AU - Bottomley, Paul A.

AU - Kogure, Kyuya

AU - Namon, Richard

AU - Alonso, Ofelia F.

PY - 1982

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N2 - Phosphorus nuclear magnetic resonance with surface coils was used to investigate the regional metabolism of the rat brain in vivo under conditions of normoxia, severe hypoxemia, partial necrosis, and partial ischemia. The results show an increase in sugar phosphate and/or inorganic phosphate with injury in accordance with in vivo assays. The technique provides a powerful means of monitoring the metabolism of stroke and its response to therapy in vivo.

AB - Phosphorus nuclear magnetic resonance with surface coils was used to investigate the regional metabolism of the rat brain in vivo under conditions of normoxia, severe hypoxemia, partial necrosis, and partial ischemia. The results show an increase in sugar phosphate and/or inorganic phosphate with injury in accordance with in vivo assays. The technique provides a powerful means of monitoring the metabolism of stroke and its response to therapy in vivo.

KW - Energy metabolism

KW - Nuclear magnetic resonance

KW - Phosphorus

KW - Surface coils

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