Cerebral energy metabolism in rats studied by phosphorus nuclear magnetic resonance using surface coils

Paul A. Bottomley; Kyuya Kogure; Richard Namon; Ofelia F. Alonso

doi:10.1016/0730-725X(82)90223-5

Cerebral energy metabolism in rats studied by phosphorus nuclear magnetic resonance using surface coils

Paul A. Bottomley, Kyuya Kogure, Richard Namon, Ofelia F. Alonso

School of Medicine

Research output: Contribution to journal › Article › peer-review

Abstract

Phosphorus nuclear magnetic resonance with surface coils was used to investigate the regional metabolism of the rat brain in vivo under conditions of normoxia, severe hypoxemia, partial necrosis, and partial ischemia. The results show an increase in sugar phosphate and/or inorganic phosphate with injury in accordance with in vivo assays. The technique provides a powerful means of monitoring the metabolism of stroke and its response to therapy in vivo.

Original language	English (US)
Pages (from-to)	81-85
Number of pages	5
Journal	Magnetic Resonance Imaging
Volume	1
Issue number	2
DOIs	https://doi.org/10.1016/0730-725X(82)90223-5
State	Published - 1982

Keywords

Energy metabolism
Nuclear magnetic resonance
Phosphorus
Surface coils

ASJC Scopus subject areas

Biophysics
Biomedical Engineering
Radiology Nuclear Medicine and imaging

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10.1016/0730-725X(82)90223-5

Cite this

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title = "Cerebral energy metabolism in rats studied by phosphorus nuclear magnetic resonance using surface coils",

abstract = "Phosphorus nuclear magnetic resonance with surface coils was used to investigate the regional metabolism of the rat brain in vivo under conditions of normoxia, severe hypoxemia, partial necrosis, and partial ischemia. The results show an increase in sugar phosphate and/or inorganic phosphate with injury in accordance with in vivo assays. The technique provides a powerful means of monitoring the metabolism of stroke and its response to therapy in vivo.",

keywords = "Energy metabolism, Nuclear magnetic resonance, Phosphorus, Surface coils",

author = "Bottomley, {Paul A.} and Kyuya Kogure and Richard Namon and Alonso, {Ofelia F.}",

note = "Funding Information: RECEWED g/6/82; ACCEPTED 9/ lO/ 82. Acknowledgements-The authors thank R.L. Nunnally, M. Santiso, and E. Martinez for their valuable assistance. This work was supported by grants GM171 72 from the NIH, NS05820-13 and NS05820-14 from the NINCDS, and from the S.B. Clayton Fund.",

year = "1982",

doi = "10.1016/0730-725X(82)90223-5",

language = "English (US)",

volume = "1",

pages = "81--85",

journal = "Magnetic Resonance Imaging",

issn = "0730-725X",

publisher = "Elsevier Inc.",

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TY - JOUR

T1 - Cerebral energy metabolism in rats studied by phosphorus nuclear magnetic resonance using surface coils

AU - Bottomley, Paul A.

AU - Kogure, Kyuya

AU - Namon, Richard

AU - Alonso, Ofelia F.

N1 - Funding Information: RECEWED g/6/82; ACCEPTED 9/ lO/ 82. Acknowledgements-The authors thank R.L. Nunnally, M. Santiso, and E. Martinez for their valuable assistance. This work was supported by grants GM171 72 from the NIH, NS05820-13 and NS05820-14 from the NINCDS, and from the S.B. Clayton Fund.

PY - 1982

Y1 - 1982

N2 - Phosphorus nuclear magnetic resonance with surface coils was used to investigate the regional metabolism of the rat brain in vivo under conditions of normoxia, severe hypoxemia, partial necrosis, and partial ischemia. The results show an increase in sugar phosphate and/or inorganic phosphate with injury in accordance with in vivo assays. The technique provides a powerful means of monitoring the metabolism of stroke and its response to therapy in vivo.

AB - Phosphorus nuclear magnetic resonance with surface coils was used to investigate the regional metabolism of the rat brain in vivo under conditions of normoxia, severe hypoxemia, partial necrosis, and partial ischemia. The results show an increase in sugar phosphate and/or inorganic phosphate with injury in accordance with in vivo assays. The technique provides a powerful means of monitoring the metabolism of stroke and its response to therapy in vivo.

KW - Energy metabolism

KW - Nuclear magnetic resonance

KW - Phosphorus

KW - Surface coils

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SP - 81

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JO - Magnetic Resonance Imaging

JF - Magnetic Resonance Imaging

SN - 0730-725X

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ER -

Cerebral energy metabolism in rats studied by phosphorus nuclear magnetic resonance using surface coils

Abstract

Keywords

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