Cerebral energy metabolism in rats studied by phosphorus nuclear magnetic resonance using surface coils

Paul A. Bottomley, Kyuya Kogure, Richard Namon, Ofelia F. Alonso

Research output: Contribution to journalArticlepeer-review

Abstract

Phosphorus nuclear magnetic resonance with surface coils was used to investigate the regional metabolism of the rat brain in vivo under conditions of normoxia, severe hypoxemia, partial necrosis, and partial ischemia. The results show an increase in sugar phosphate and/or inorganic phosphate with injury in accordance with in vivo assays. The technique provides a powerful means of monitoring the metabolism of stroke and its response to therapy in vivo.

Original languageEnglish (US)
Pages (from-to)81-85
Number of pages5
JournalMagnetic Resonance Imaging
Volume1
Issue number2
DOIs
StatePublished - 1982

Keywords

  • Energy metabolism
  • Nuclear magnetic resonance
  • Phosphorus
  • Surface coils

ASJC Scopus subject areas

  • Biophysics
  • Biomedical Engineering
  • Radiology Nuclear Medicine and imaging

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