Cerebral blood flow measurements by magnetic resonance imaging bolus tracking: Comparison with [15O]H2O positron emission tomography in humans

Leif Østergaard, Peter Johannsen, Peter Høst-Poulsen, Peter Vestergaard-Poulsen, Helle Asboe, Antony D. Gee, Søren B. Hansen, Georg E. Cold, Albert Gjedde, Garsten Gyldensted

Research output: Contribution to journalReview articlepeer-review

Abstract

In six young, healthy volunteers, a novel method to determine cerebral blood flow (CBF) using magnetic resonance (MR) bolus tracking was compared with [15O]H2O positron emission tomography (PET). The method yielded parametric CBF images with tissue contrast in good agreement with parametric PET CBF images. Introducing a common conversion factor, MR CBF values could be converted into absolute flow rates, allowing comparison of CBF values among normal subjects.

Original languageEnglish (US)
Pages (from-to)935-940
Number of pages6
JournalJournal of Cerebral Blood Flow and Metabolism
Volume18
Issue number9
DOIs
StatePublished - Sep 1998

Keywords

  • Cerebral blood flow
  • Dynamic magnetic resonance imaging
  • Humans susceptibility contrast

ASJC Scopus subject areas

  • Neurology
  • Clinical Neurology
  • Cardiology and Cardiovascular Medicine

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