TY - JOUR
T1 - Cerebral and tissue oximetry
AU - Steppan, Jochen
AU - Hogue, Charles W.
N1 - Funding Information:
Supported in part by a grant to Dr. Hogue from the National Institutes of Health ( R01 HL092259-1 ).
Funding Information:
Charles W Hogue, Jr.: Research funding from Covidien, Inc (Boulder, CO), Advisory Board Membership for Ornim (Israel), Data and Safety Montioring Board , CSL Behring (King of Prussia, PA). The IRB number is NA00077079 and the clinicalTrials.gov identifier is NCT01765504.
Publisher Copyright:
© 2014 Elsevier Ltd. All rights reserved.
PY - 2014
Y1 - 2014
N2 - The use of near-infrared spectroscopy (NIRS) has been increasingly adopted in cardiac surgery to measure regional cerebral oxygen saturation. This method takes advantage of the fact that light in the near-infrared spectrum penetrates tissue, including bone and muscle. Sensors are placed at fixed distances from a light emitter, and algorithms subtract superficial light absorption from deep absorption to provide an index of tissue oxygenation. Although the popularity of NIRS monitoring is growing, definitive data that prove outcome benefits with its use remain sparse. Therefore, widespread, routine use of NIRS as a standard-of-care monitor cannot be recommended at present. Recent investigations have focused on the use of NIRS in subgroups that may benefit from NIRS monitoring, such as pediatric patients. Furthermore, a novel application of processed NIRS information for monitoring cerebral autoregulation and tissue oxygenation (e.g., kidneys and the gut) is promising.
AB - The use of near-infrared spectroscopy (NIRS) has been increasingly adopted in cardiac surgery to measure regional cerebral oxygen saturation. This method takes advantage of the fact that light in the near-infrared spectrum penetrates tissue, including bone and muscle. Sensors are placed at fixed distances from a light emitter, and algorithms subtract superficial light absorption from deep absorption to provide an index of tissue oxygenation. Although the popularity of NIRS monitoring is growing, definitive data that prove outcome benefits with its use remain sparse. Therefore, widespread, routine use of NIRS as a standard-of-care monitor cannot be recommended at present. Recent investigations have focused on the use of NIRS in subgroups that may benefit from NIRS monitoring, such as pediatric patients. Furthermore, a novel application of processed NIRS information for monitoring cerebral autoregulation and tissue oxygenation (e.g., kidneys and the gut) is promising.
KW - Anesthesia
KW - Cardiac surgery
KW - Cerebral autoregulation
KW - Monitor
KW - NIRS
KW - Near-infrared spectroscopy
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U2 - 10.1016/j.bpa.2014.09.002
DO - 10.1016/j.bpa.2014.09.002
M3 - Review article
C2 - 25480772
AN - SCOPUS:84927913830
SN - 1521-6896
VL - 28
SP - 429
EP - 439
JO - Best Practice and Research: Clinical Anaesthesiology
JF - Best Practice and Research: Clinical Anaesthesiology
IS - 4
ER -