Ceramide and cerebroside from the stem bark of Ficus mucuso (Moraceae)

Jean Jules Kezetas Bankeu, Sufyan Awad Alkarim Mustafa, Anar Sahib Gojayev, Bruno Djakou Lenta, Didérot Tchamo Noungoué, Silvère Augustin Ngouela, Khalid Asaad, Mohammed Iqbal Choudhary, Sean Prigge, Akif Alekper Guliyev, Augustin Ephrem Nkengfack, Etienne Tsamo, Muhammad Shaiq Ali

Research output: Contribution to journalArticlepeer-review

Abstract

Two new sphingolipids mucusamide (1) and mucusoside (2) have been isolated from methanol soluble part of the stem bark of Ficus mucuso WELW., together with fifteen known secondary metabolites including cellobiosylsterol (3), β-sitosterol (4), stigmasterol (5), β-sitosterol 3-O-β-D- glucopyranoside (6), lupeol acetate (7), ursolic acid (8), procatechuic acid (9), 2-methyl-5,7-dihydroxychromone 8-C-β-D-glucoside (10), apigenin (11), (-)-epicatechin (12), (+)-catechin (13), N-benzoyl-L-phenylalanilol (14), α-acetylamino-phenylpropyl α-benzoylaminophenylpropionate (15), asperphenamate (16) and bejaminamide (17). Structures of compounds 1 and 2 were elucidated by spectroscopic analysis and chemical methods.

Original languageEnglish (US)
Pages (from-to)1661-1665
Number of pages5
JournalChemical and Pharmaceutical Bulletin
Volume58
Issue number12
DOIs
StatePublished - Dec 2010

Keywords

  • Ficus mucuso
  • Moraceae
  • Mucusamide
  • Mucusoside
  • Sphingolipid

ASJC Scopus subject areas

  • Chemistry(all)
  • Drug Discovery

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