TY - JOUR
T1 - Central Ocular Motor Abnormalities in Duane's Retraction Syndrome
AU - Gourdeau, Alain
AU - Miller, Neil
AU - Zee, David
AU - Morris, Jacqueline
PY - 1981/10
Y1 - 1981/10
N2 - Duane's retraction syndrome (DRS) is a congenital eye movement disorder characterized by marked limitation or absence of abduction, variable limitation of adduction, and narrowing of the palpebral fissure with retraction of the globe on attempted adduction. We have recently recorded and quantitated ocular motility in five patients with unilateral DRS. In all patients, abduction of the affected eye was greatly limited, whereas adduction was limited to a lesser degree. Abnormalities in saccadic velocities were found in both the affected eye and the sound eye. Results of testing of the vestibulo-ocular reflex, optokinetic nystagmus, and optokinetic afternystagmus showed notable asymmetry. Our results suggest that DRS is produced by a primary brainstem abnormality involving premotor structures.
AB - Duane's retraction syndrome (DRS) is a congenital eye movement disorder characterized by marked limitation or absence of abduction, variable limitation of adduction, and narrowing of the palpebral fissure with retraction of the globe on attempted adduction. We have recently recorded and quantitated ocular motility in five patients with unilateral DRS. In all patients, abduction of the affected eye was greatly limited, whereas adduction was limited to a lesser degree. Abnormalities in saccadic velocities were found in both the affected eye and the sound eye. Results of testing of the vestibulo-ocular reflex, optokinetic nystagmus, and optokinetic afternystagmus showed notable asymmetry. Our results suggest that DRS is produced by a primary brainstem abnormality involving premotor structures.
KW - Duane's retraction syndrome
KW - optokinetic nystagmus
KW - saccades
KW - vestibulo-ocular reflex
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U2 - 10.1001/archopht.1981.03930020683011
DO - 10.1001/archopht.1981.03930020683011
M3 - Article
C2 - 7295131
AN - SCOPUS:0019487451
SN - 0003-9950
VL - 99
SP - 1809
EP - 1810
JO - Archives of ophthalmology
JF - Archives of ophthalmology
IS - 10
ER -