Central nervous system cancers

Louis Burt Nabors; Mario Ammirati; Philip J. Bierman; Henry Brem; Nicholas Butowski; Marc C. Chamberlain; Lisa M. DeAngelis; Robert A. Fenstermaker; Allan Friedman; Mark R. Gilbert; Deneen Hesser; Matthias Holdhoff; Larry Junck; Ronald Lawson; Jay S. Loeffler; Moshe H. Maor; Paul L. Moots; Tara Morrison; Maciej M. Mrugala; Herbert B. Newton; Jana Portnow; Jeffrey J. Raizer; Lawrence Recht; Dennis C. Shrieve; Allen K. Sills; David Tran; Nam Tran; Frank D. Vrionis; Patrick Y. Wen; Maria Ho

doi:10.6004/jnccn.2013.0132

Central nervous system cancers

Louis Burt Nabors, Mario Ammirati, Philip J. Bierman, Henry Brem, Nicholas Butowski, Marc C. Chamberlain, Lisa M. DeAngelis, Robert A. Fenstermaker, Allan Friedman, Mark R. Gilbert, Deneen Hesser, Matthias Holdhoff, Larry Junck, Ronald Lawson, Jay S. Loeffler, Moshe H. Maor, Paul L. Moots, Tara Morrison, Maciej M. Mrugala, Herbert B. NewtonJana Portnow, Jeffrey J. Raizer, Lawrence Recht, Dennis C. Shrieve, Allen K. Sills, David Tran, Nam Tran, Frank D. Vrionis, Patrick Y. Wen, Maria Ho

School of Medicine

Research output: Contribution to journal › Review article › peer-review

38 Scopus citations

Abstract

Primary and metastatic tumors of the central nervous system are a heterogeneous group of neoplasms with varied outcomes and management strategies. Recently, improved survival observed in 2 randomized clinical trials established combined chemotherapy and radiation as the new standard for treating patients with pure or mixed anaplastic oligodendroglioma harboring the 1p/19q codeletion. For metastatic disease, increasing evidence supports the efficacy of stereotactic radiosurgery in treating patients with multiple metastatic lesions but low overall tumor volume. These guidelines provide recommendations on the diagnosis and management of this group of diseases based on clinical evidence and panel consensus. This version includes expert advice on the management of low-grade infiltrative astrocytomas, oligodendrogliomas, anaplastic gliomas, glioblastomas, medulloblastomas, supratentorial primitive neuroectodermal tumors, and brain metastases. The full online version, available at NCCN. org, contains recommendations on additional subtypes.

Original language	English (US)
Pages (from-to)	1114-1151
Number of pages	38
Journal	JNCCN Journal of the National Comprehensive Cancer Network
Volume	11
Issue number	9
DOIs	https://doi.org/10.6004/jnccn.2013.0132
State	Published - Sep 1 2013

ASJC Scopus subject areas

Oncology

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10.6004/jnccn.2013.0132

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Burt Nabors, L., Ammirati, M., Bierman, P. J., Brem, H., Butowski, N., Chamberlain, M. C., DeAngelis, L. M., Fenstermaker, R. A., Friedman, A., Gilbert, M. R., Hesser, D., Holdhoff, M., Junck, L., Lawson, R., Loeffler, J. S., Maor, M. H., Moots, P. L., Morrison, T., Mrugala, M. M., ... Ho, M. (2013). Central nervous system cancers. JNCCN Journal of the National Comprehensive Cancer Network, 11(9), 1114-1151. https://doi.org/10.6004/jnccn.2013.0132

Burt Nabors, L, Ammirati, M, Bierman, PJ, Brem, H, Butowski, N, Chamberlain, MC, DeAngelis, LM, Fenstermaker, RA, Friedman, A, Gilbert, MR, Hesser, D, Holdhoff, M, Junck, L, Lawson, R, Loeffler, JS, Maor, MH, Moots, PL, Morrison, T, Mrugala, MM, Newton, HB, Portnow, J, Raizer, JJ, Recht, L, Shrieve, DC, Sills, AK, Tran, D, Tran, N, Vrionis, FD, Wen, PY & Ho, M 2013, 'Central nervous system cancers', JNCCN Journal of the National Comprehensive Cancer Network, vol. 11, no. 9, pp. 1114-1151. https://doi.org/10.6004/jnccn.2013.0132

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abstract = "Primary and metastatic tumors of the central nervous system are a heterogeneous group of neoplasms with varied outcomes and management strategies. Recently, improved survival observed in 2 randomized clinical trials established combined chemotherapy and radiation as the new standard for treating patients with pure or mixed anaplastic oligodendroglioma harboring the 1p/19q codeletion. For metastatic disease, increasing evidence supports the efficacy of stereotactic radiosurgery in treating patients with multiple metastatic lesions but low overall tumor volume. These guidelines provide recommendations on the diagnosis and management of this group of diseases based on clinical evidence and panel consensus. This version includes expert advice on the management of low-grade infiltrative astrocytomas, oligodendrogliomas, anaplastic gliomas, glioblastomas, medulloblastomas, supratentorial primitive neuroectodermal tumors, and brain metastases. The full online version, available at NCCN. org, contains recommendations on additional subtypes.",

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AU - Burt Nabors, Louis

AU - Ammirati, Mario

AU - Bierman, Philip J.

AU - Brem, Henry

AU - Butowski, Nicholas

AU - Chamberlain, Marc C.

AU - DeAngelis, Lisa M.

AU - Fenstermaker, Robert A.

AU - Friedman, Allan

AU - Gilbert, Mark R.

AU - Hesser, Deneen

AU - Holdhoff, Matthias

AU - Junck, Larry

AU - Lawson, Ronald

AU - Loeffler, Jay S.

AU - Maor, Moshe H.

AU - Moots, Paul L.

AU - Morrison, Tara

AU - Mrugala, Maciej M.

AU - Newton, Herbert B.

AU - Portnow, Jana

AU - Raizer, Jeffrey J.

AU - Recht, Lawrence

AU - Shrieve, Dennis C.

AU - Sills, Allen K.

AU - Tran, David

AU - Tran, Nam

AU - Vrionis, Frank D.

AU - Wen, Patrick Y.

AU - Ho, Maria

PY - 2013/9/1

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Central nervous system cancers

Abstract

ASJC Scopus subject areas

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