Central mutation databases - A review

Christopher J. Porter, C. Conover Talbot, A. Jamie Cuticchia

Research output: Contribution to journalArticle


The Internet has been a key component in the coordination of the diverse group of scientists involved in the Human Genome Project. Nowhere has this contribution been more critical than in the maintenance and exchange of information about genetic variation and mutation. Whereas the majority of DNA sequence is generated and stored by a relatively few sites, a far greater number of researchers investigate the variations in that sequence from sites scattered worldwide. It falls to central databases to utilize the Internet to assemble data from these sites and make them available to the greater human genomic community.

Original languageEnglish (US)
Pages (from-to)36-44
Number of pages9
JournalHuman mutation
Issue number1
StatePublished - Jan 19 2000


  • Central databases
  • MDI
  • Mutation database
  • Variation

ASJC Scopus subject areas

  • Genetics
  • Genetics(clinical)

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