TY - JOUR
T1 - Cellular Mechanisms of Resolution of Drusen After Laser Coagulation
T2 - An Experimental Study
AU - Duvall, Josephine
AU - Tso, Mark O.M.
PY - 1985/5
Y1 - 1985/5
N2 - Naturally occurring drusen in two eyes of a rhesus monkey resolved after the application to the retina of mild laser coagulation. Clinically, resolution took place approximately nine days following treatment. The cellular mechanism for resolution was observed by light and electron microscopy over a time period of three days to six weeks after treatment. A previously unidentified phagocytic cell, probably derived from the pericyte of the choriocapillaris, was observed to remove drusenoid material after laser photocoagulation. The cell appeared to be analogous to the mesangial cell of the renal glomerulus.
AB - Naturally occurring drusen in two eyes of a rhesus monkey resolved after the application to the retina of mild laser coagulation. Clinically, resolution took place approximately nine days following treatment. The cellular mechanism for resolution was observed by light and electron microscopy over a time period of three days to six weeks after treatment. A previously unidentified phagocytic cell, probably derived from the pericyte of the choriocapillaris, was observed to remove drusenoid material after laser photocoagulation. The cell appeared to be analogous to the mesangial cell of the renal glomerulus.
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U2 - 10.1001/archopht.1985.01050050086024
DO - 10.1001/archopht.1985.01050050086024
M3 - Article
C2 - 4039560
AN - SCOPUS:0021824924
SN - 0003-9950
VL - 103
SP - 694
EP - 703
JO - Archives of ophthalmology
JF - Archives of ophthalmology
IS - 5
ER -