Cellular mechanisms of IgE antibody response

K. Ishizaka

Research output: Contribution to journalArticlepeer-review

Abstract

Secondary anti hapten IgE antibody response was observed in vitro using rabbit mesenteric lymph node cells primed with DNP Asc or DNP Rag included in alum. Analysis of immunocompetent cells involved in the anti hapten IgE and IgG antibody responses in this system revealed that B cells for IgE antibody were different from B cells for IgG antibody response. Evidence was obtained that helper T cells collaborating with IgE B cells may be different from the helper cells involved in the IgG antibody response.

Original languageEnglish (US)
Pages (from-to)255-270
Number of pages16
JournalInternational archives of allergy and applied immunology
Volume49
Issue number1-2
DOIs
StatePublished - 1975

ASJC Scopus subject areas

  • Immunology and Allergy

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