Cellular deposits on intraocular lenses

A. Puck, Mark O M Tso, B. Yue

Research output: Contribution to journalArticle

Abstract

We examined cellular deposits on 14 intraocular lenses (IOL) that were removed after implantation for a variety of clinical reasons. Five of the lenses were cultured to evaluate the growth potential of preexisting cells on the IOLs. The most common cells found were iris pigment epithelial cells. The thickest membranes were probably formed by iris stromal cells. Other cellular deposits included macrophages, multinucleated foreign body giant cells, lens epithelial cells, squamous epithelial ingrowth, red blood cells, uveal melanocytes, and vitreous strands. Cells around the IOL had only limited growth in tissue culture. We propose that a continuous influx of inflammatory cells in conjunction with a disruption of the blood-aqueous barrier may be an important pathogenetic mechanism for the production of thick secondary membranes around an IOL.

Original languageEnglish (US)
Pages (from-to)54-60
Number of pages7
JournalActa Ophthalmologica
Volume63
Issue numberSUPPL. 170
StatePublished - 1985

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Intraocular Lenses
Epithelial Cells
Iris
Lenses
Blood-Aqueous Barrier
Foreign Body Giant Cells
Membranes
Melanocytes
Stromal Cells
Growth
Erythrocytes
Macrophages

ASJC Scopus subject areas

  • Ophthalmology
  • Medicine(all)

Cite this

Puck, A., Tso, M. O. M., & Yue, B. (1985). Cellular deposits on intraocular lenses. Acta Ophthalmologica, 63(SUPPL. 170), 54-60.

Cellular deposits on intraocular lenses. / Puck, A.; Tso, Mark O M; Yue, B.

In: Acta Ophthalmologica, Vol. 63, No. SUPPL. 170, 1985, p. 54-60.

Research output: Contribution to journalArticle

Puck, A, Tso, MOM & Yue, B 1985, 'Cellular deposits on intraocular lenses', Acta Ophthalmologica, vol. 63, no. SUPPL. 170, pp. 54-60.
Puck, A. ; Tso, Mark O M ; Yue, B. / Cellular deposits on intraocular lenses. In: Acta Ophthalmologica. 1985 ; Vol. 63, No. SUPPL. 170. pp. 54-60.
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